From: Using water–solvent systems to estimate in vivo blood–tissue partition coefficients
Process | p | R2 | c0 | c1 |
---|---|---|---|---|
Blood–brain | 0.06 | 0.64 | 0.553 | 0.171 |
Blood–muscle | 0.7 | 0.03 | 0.082 | 0.008 |
Blood–liver | 0.6 | 0.07 | 0.293 | 0.026 |
Blood–lung | 0.3 | 0.27 | 0.272 | 0.097 |
Blood–kidney | 0.6 | 0.07 | 0.495 | 0.032 |
Blood–heart | 0.3 | 0.31 | 0.134 | 0.070 |
Blood–skin | 0.003 | 0.92 | −0.100 | 0.161 |
Blood–fat | 0.01 | 0.82 | 0.088 | 0.324 |
Water–skin | 0.0003 | 0.97 | 0.537 | 0.415 |
Skin-permeation | 0.0004 | 0.97 | −5.402 | 0.545 |