Fig. 2From: De-novo design, synthesis and evaluation of novel 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives as HIV-1 reverse transcriptase inhibitorsStructure of tetrahydroisoquinolines (2a, 2b, 2c and 2e) and related analogue (2d) as potent inhibitor of HIV-1 and HIV-1 RT along with proposed pharmacophoric model (2f) and designed prototypes (5 and 8)Back to article page