Slow release anti-fungal skin formulations based on citric acid intercalated layered double hydroxides nanohybrids

Table 1 Inhibitory activity of test compounds against C. albicans, C. glabrata and C. tropicalis

Substances tested	Visually inspected growth
	Candida albicans		Candida glabrata		Candida tropicalis
	After 24 h	After 48 h	After 24 h	After 48 h	After 24 h	After 48 h
Fluconazole	0	0	0	0	0	+1
Pure citric acid	0	+2	0	+2	0	+2
Citrate-LDH	0	0	0	0	0	+1
Body lotion matrix	+1	+2	+2	+2	+1	+2
Citrate-LDH incorporated lotion	0	0	0	0	0	+1

The study of slow release antifungal activity is based on visual observation of the fungal growth in a Muller Hinton culture media and the criteria used is given below
+2: Growth is equals to that of the negative control
+1: Growth approximately 50 % that of the negative control
0: No visible growth at all

ISSN: 2661-801X