|
Compound
|
Alkyl β-D-glucopyranosides
b
|
Control surfactants
b
|
|---|
|
4a
|
4b
|
4c
|
4d
|
4e
|
4f
|
4g
|
5
|
C14G1
|
β-OTG
|
C7G1
|
|---|
|
Hydrophobic tail
|
C
8
H
17
|
C
10
H
21
|
C
12
H
25
|
C
14
H
29
|
C
16
H
33
|
C
2
H
4
C
6
F
13
|
C
2
H
4
C
8
F
17
|
C
8
H
17
|
C
14
H
29
|
C
8
H
17
|
C
7
H
15
|
|
IC
50
value [μM]
|
1198
|
171
|
89
|
53
|
24
|
*
|
*
|
663
|
67
|
163
|
*
|
-
aThe inhibitory concentration 50% (IC50) in μM is defined as the concentration of experimental compound required to inhibited 50% of the conversion of MTS to formazan, as compared with the absorbance produced by untreated cells after 16 h of incubation.
-
bPlease see Scheme 1 for the chemical structures and corresponding abbreviations for the alkyl β-D-glucopyranosides and the control surfactants.
- *Cytotoxicity was <50% at the highest compound concentration tested (2000 μM) and therefore their IC50 values could not be determined.
