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Table 2 Effect of steroids and triterpenoids from supercritical carbon dioxide extracts of H. polyrhizus and H. undatus against cell viability of different cancer cell lines

From: Chemical composition and in vitroevaluation of the cytotoxic and antioxidant activities of supercritical carbon dioxide extracts of pitaya (dragon fruit) peel

Compound

IC50(μM)a

 

PC3

Bcap-37

MGC-803

α-Amyrin

>100b

>100

>100

β-Amyrin

73.2 ± 1.02

78.4 ± 0.93

51.9 ± 0.87

β-Sitosterol

74.4 ± 0.65

58.2 ± 0.44

43.8 ± 0.63

Stigmast-4-en-3-one

65.4 ± 1.13

79.3 ± 0.49

56.9 ± 0.81

ADMc

1.09 ± 0.18

1.34 ± 0.30

0.83 ± 0.22

  1. aAgent concentration (μM) that inhibited cell growth by 50% at 72 h after treatment.
  2. bWhen 50% inhibition could not reached at the highest concentration, then >100 μM was given.
  3. cAdriamycin, positive control.