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Table 1 Antifungal activities of the title compounds 5–9 at 50 mg/L

From: Synthesis and antifungal activities of novel nicotinamide derivatives containing 1,3,4-oxadiazole

Compound

Inhibition ratea(%)

 

G. zeae

F. oxysporum

C.mandshurica

5

17.9 ± 1.6

10.3 ± 0.9

15.5 ± 0.7

6

33.2 ± 1.7

21.3 ± 1.1

30.3 ± 1.9

7a

19.0 ± 2.9

55.2 ± 0.6

53.1 ± 1.3

7b

46.4 ± 1.3

51.1 ± 1.0

49.9 ± 1.1

7c

39.6 ± 1.3

31.9 ± 1.4

44.9 ± 0.7

7d

27.9 ± 0.2

12.5 ± 1.7

17.3 ± 1.0

8

53.0 ± 2.4

58.9 ± 4.3

52.8 ± 1.3

9a

43.2 ± 0.6

63.2 ± 0.9

59.8 ± 1.4

9b

58.3 ± 2.7

53.3 ± 3.9

54.5 ± 1.2

9c

45.6 ± 1.8

47.6 ± 1.0

49.3 ± 1.1

9d

35.4 ± 1.9

17.2 ± 0.3

34.3 ± 0.9

Hymexazolb

55.54 ± 3.9

56.12 ± 2.1

49.61 ± 3.2

Carbendazolb

100 ± 3.74

100 ± 4.9

100 ± 5.23

  1. aAverage of three replicates, bThe commercial agricultural fungicide hymexazol and carbendazol were used for activity comparison.