Table 2 SMART filtering number of failures (%) using SMART filter website
From: Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv)
Filters | Rep_dataset | NRep_dataset | Novartis (283) | TB drugs (13) | US Antibiotic* | US FDA** | JH FDA# | Natural Product## |
|---|---|---|---|---|---|---|---|---|
GSK (%) | 197 (14.5) | 196 (16.3) | 20 (7.1) | 1 (7.7) | 57 (35) | 143 (13.7) | 401 (14.9) | 125 (15.6) |
Pfizer LINT (%) | 609 (44.9) | 532 (44.1) | 135 (47.7) | 6 (46.1) | 93 (57.0) | 516 (49.6) | 1264 (46.9) | 304 (38.0) |
Abbott ALARM (%) | 1064 (78.5) | 948 (78.6) | 243 (85.9) | 7 (53.8) | 144 (88.3) | 688 (66.1) | 1442 (53.5) | 521 (65.1) |