Intramolecular H-bonding interaction in angular 3-π-EWG substituted imidazo[1,2-a]pyridines contributes to conformational preference

Table 2 Topological Parameters for BCP found between H-5 and O for conformers 6a and 7a and values for an electrostatic hydrogen bond (feature values)

Topological Parameter	Compound 6a	Compound 7a	Feature Value
ρ_BCP	0.017	0.014	0.002-0.040
∇²ρ_BCP	0.060	0.049	0.024-0.139
d H· · · Y	2.26	2.32	H· · · O < 2.61

ISSN: 2661-801X