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Table 1 Anti- Candida activity of the target compounds 5a-k against Candida albicans and Candida tropicalis

From: 1-Aryl-3-(1H-imidazol-1-yl)propan-1-ol esters: synthesis, anti-Candidapotential and molecular modeling studies

Compound no Candida albicans Candida tropicalis
  DIZ ± SD* MIC (μmol/mL)** DIZ ± SD* MIC (μmol/mL)**
5a 17 ± 1.1 0.0833 13 ± 0.9 0.3331
5b 16 ±1.1 0.6662 14 ±1.0 0.3331
5c 16 ±1.0 0.6742 14 ± 0.9 0.3371
5d 14 ± 0.5 0.3523 16 ±1.1 0.3523
5e 16 ±1.6 0.3854 16 ± 0.6 0.3854
5f 16 ± 0.9 0.3902 11 ± 0.9 0.7803
5g 14 ± 0.0 0.6678 14 ± 0.0 0.3339
5h 17 ± 0.9 0.4218 17 ± 0.8 0.4218
5i 14 ± 0.0 0.8134 16 ± 1.0 0.8134
5j 14 ± 0.0 0.8134 19 ± 1.0 0.4067
5k 16 ± 0.6 0.7208 14 ± 0.5 0.3604
Fluconazole 15 ± 0.5 >1.6325 16 ± 0.5 >1.6325
  1. *The arithmetic mean of the inhibition zone diameters in mean ± standard deviation. **The lowest concentration of the compound that produced 50-80% microbial growth inhibition (μmol/mL).