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Table 1 IC 50 effect of tested compounds on oxidative burst of whole blood, isolated PMNs, T-cell proliferation and IL-2 cytokine

From: In-vitro immunomodulatory and anti-cancerous activities of biotransformed products of Dianabol through Azadirachta indica and its molecular docking studies

Comp. Code Oxidative burst IC50(μM) on T- Cell proliferation IC50 (μM) IC50IL-2 (μM)
Whole blood PMNs
1 >333.33 >166.67 >166.67 >166.67
2 >331.13 >165.56 <10.33 16.89 ± 1.32
3 >328.95 >164.47 42.11 ± 11.51 49.34 ± 1.32
Control Aa 11.2 ± 1.9 2.8 ± 0.8 - -
Control Bb - - 0.2 <0.5
  1. aIbuprofen; bPrednisolone.