In-vitro immunomodulatory and anti-cancerous activities of biotransformed products of Dianabol through Azadirachta indica and its molecular docking studies

Table 1 IC ₅₀ effect of tested compounds on oxidative burst of whole blood, isolated PMNs, T-cell proliferation and IL-2 cytokine

Comp. Code	Oxidative burst IC₅₀(μM) on		T- Cell proliferation IC₅₀ (μM)	IC₅₀IL-2 (μM)
Comp. Code	Whole blood	PMNs	T- Cell proliferation IC₅₀ (μM)	IC₅₀IL-2 (μM)
1	>333.33	>166.67	>166.67	>166.67
2	>331.13	>165.56	<10.33	16.89 ± 1.32
3	>328.95	>164.47	42.11 ± 11.51	49.34 ± 1.32
Control A^a	11.2 ± 1.9	2.8 ± 0.8	-	-
Control B^b	-	-	0.2	<0.5

ISSN: 2661-801X