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Table 5 The MICs (μg/mL) of selected newly synthesized compounds against the tested microorganisms

From: Approaches towards the synthesis of a novel class of 2-amino-5-arylazonicotinate, pyridazinone and pyrido[2,3-d]pyrimidine derivatives as potent antimicrobial agents

Compound No. The minimum inhibitory concentration (MIC) in μg/mL
E. coli P. aeruginosa B. subtilis S. aureus C. albicans
1a 50 - 50 - 12.5
2a - - 125 100 -
2g - - 100 - -
8a - - 12.5 - -
8b - - 25 - -
8c - - 50 - -
8d -   25 -  
8e - - 25 - -
8g - - 25 - -
10a - - 50 - -
10b - - 25 - -
10c - - 12.5 - -
11b - - 100 - -
13a - - 100 - -
13b - - 100 - -
15a - - 100 - -
15b - - 50 - -
16 0 0 50 100 -
a Ampicillin 6.25 - 12.5 12.5 -
b Cycloheximide - - - - -
  1. a Ampicillin antibacterial drug, b cycloheximide antifungal drug, – not measured.