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Table 7 Assay results of moxifloxacin and prednisolone in commercial eye drops

From: Stability indicating HPLC method for the simultaneous determination of moxifloxacin and prednisolone in pharmaceutical formulations

Products

Ingredient

Label value (mg per mL)

% Recovery ±RSD (%)

Eye drops

Occumox P

Moxifloxacin

5

100.3 ± 0.3

Prednisolone

10

99.0 ± 0.7

Moftrex P

Moxifloxacin

5

100.7 ± 0.1

 

Prednisolone

10

98.9 ±0.7

  1. n = Average of 10 determinations, Chromatographic conditions: mobile phase Methanol: 18 mM phosphate buffer 62:38, v/v, pH 2.8, Column BDS Hypersil C8 (250 X 4.6, 5 μm), flow rate 1.5 mL min-1, injection volume 20 μL, wavelength 254 nm.