Table 3 Summary of stress degradation studies of chloramphenicol (2).

Acidic hydrolysis^a

1N HCl

23.75

0.01, 0.04

5N HCl

69.36

0.01, 0.04, 0.81

Basic hydrolysis^a

0.1N NaOH

100

0.01, 0.44, 0.79

1N NaOH

100

0.01, 0.04, 0.81

5N NaOH

100

0.01, 0.02, 0.04, 0.48

Neutral hydrolysis^a

H₂O

14.35

0.01

Wet heating^a

28.44

0.01, 0.79

Dry heating

24

0.01, 0.79

Photochemical

26.029

0.01,0.09,0.15, 0.27,0.44,0.81,0.85

Oxidation

35%v/v H₂O₂ ^a

4.129

0.01, 0.12, 0.31

Oxidation at room temp

9.58

0.01, 0.12, 0.31