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Table 5 Determination of the studied drugs in Dimetrol® suspension by the updated PLS model and statistical comparison with the reported RP-HPLC method

From: Simultaneous determination of some antiprotozoal drugs in different combined dosage forms by mean centering of ratio spectra and multivariate calibration with model updating methods

Parameters

Updated PLS model

 

DF

METB

Dimetrol ® suspension a

(B.No.906001)

101.19 ± 1.327

99.59 ± 0.981

Standard addition b

99.95 ± 1.233

100.55 ± 1.159

Degree of freedom F-test

(5.050) c

10

10

 

0.738

1.026

Degree of freedom

10

10

Student's -t test

(2.228) c

0.200

0.444

  1. a: Average of 6 determinations
  2. b: Average of 3 determinations
  3. c: The values in the parenthesis are the corresponding theoretical values at p = 0.05