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Table 2 Effect on cyclooxygenase-1 activity

From: New analogues of 13-hydroxyocatdecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity

Compound

COX-1 activity

IC50 ± S.E.M (μM)a

3

2.2 ± 0.7

4

12.1 ± 2.3

7

1.3 ± 0.5

8

6.5 ± 0.2

9

8.1 ± 1.7

  1. a n = 3-4 in all experiments.
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BMC Chemistry

ISSN: 2661-801X

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