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Table 3 Application of the proposed method to the determination of the studied drugs in the pure form

From: Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma

Parameter

Concentration taken

(ng/mL)

Concentration found

(ng/mL)

% Found

Reference method [4]

1- MEB

10

10.06

100.56

100.46

 

20

20.29

101.44

99.53

 

30

30.12

100.40

100.15

 

40

39.74

99.36

 
 

50

49.78

99.55

 
 

60

60.01

100.02

 
 

80

79.46

99.33

 
 

100

100.54

100.54

 

   X'

  

100.22

100.04

   ± S.D.

  

0.757

0.473

   t-test

 

0.0.379 (1.833)

  

   F-value

 

2.55 (4.74)

  

2- SUL

10

10.08

100.78

100.9

 

20

19.80

99.00

99.0

 

30

30.10

100.34

100.3

 

40

40.05

100.13

 
 

50

50.00

100.00

 
 

60

59.71

99.52

 
 

80

80.43

100.53

 
 

100

99.82

99.825

 

   X'

  

99.96

100.0

   ± S.D.

  

0.390

0.92

   t-test

 

0.08 (1.833)

  

   F-value

 

2.41 (4.74)

  
  1. Values between parenthesis are the tabulated t and F values, respectively at p = 0.05.