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Table 5 Effect of temperature on the kinetic parameters of SER.

From: Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids

Temperature (°C)

K (min.-1)

T1/2(min.)

Ea (K.Cal.Mol-1)

50°C

0.018

38.58

 

60°C

0.023

30.13

5.33

70°C

0.033

21.00

8.19

80°C

0.042

16.63

5.62

   

X' = 6.38