Skip to main content

Table 3 Validation of the proposed methods for the determination of PG pure form

From: Utility of certain nucleophilic aromatic substitution reactions for the assay of pregabalin in capsules

Parameter Method I Method II
  Pregabalin concentration (μg mL-1 ) Pregabalin concentration (μg mL-1 )
  8.0 15.0 20 2 4 6
Intraday  
% Found 100.37 100.77 100.76 98.72 101.75 98.34
  101.23 98.20 101.02 101.29 98.24 100.89
  98.94 101.80 99.24 101.43 99.72 101.48
Mean () 100.18 100.26 100.34 100.48 99.90 100.24
S.D. 1.16 1.85 0.96 1.53 1.76 1.67
% RSD 1.16 1.85 0.96 1.52 1.76 1.67
% Error 0.67 1.07 0.55 0.88 1.02 0.96
Inter-day  
% Found 100.47 99.09 100.32 99.37 98.90 102.26
  99.53 101.48 99.71 100.63 101.10 100.75
  100.78 100.91 101.16 98.95 101.10 99.25
Mean () 100.26 100.49 100.40 99.65 100.37 100.75
S.D. 0.65 1.25 0.73 0.87 1.27 1.51
% RSD 0.65 1.24 0.73 0.88 1.27 1.49
% Error 0.38 0.72 0.42 0.51 0.73 0.86
  1. Each result is the average of three separate determinations.
Back to article page

BMC Chemistry

ISSN: 2661-801X

Contact us