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Table 3 Application of the proposed method for the analysis of ebastine in pure form

From: Validated stability indicating liquid chromatographic determination of ebastine in pharmaceuticals after pre column derivatization: Application to tablets and content uniformity testing

Proposed method

Comparison method [4]

Amount taken (μg/ml)

Amount found (μg/ml)

% Recovery

% Recovery

0.3

0.2976

99.21

100.62

0.5

0.5031

100.62

99.15

0.7

0.7030

100.43

99.34

1.0

0.9972

99.72

 

2.0

2.0148

100.74

 

3.0

3.0072

100.24

 

4.0

3.9912

99.78

 

5.0

4.981

99.62

 

6.0

6.0264

100.44

 

Xˉ ± SD

 

100.09 ± 0.52

99.70 ± 0.79

Student's t test

 

0.61(1.86)*

 

Variance ratio F test

 

2.3(5.25)*

 
  1. *Figures between parentheses are the tabulated t and F values at p = 0.05 [20].*
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BMC Chemistry

ISSN: 2661-801X

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