Figure 7
Typical chromatograms of EBS-Zn2+ complex in presence of co-administered drugs. A. Typical chromatogram showing EBS-Zn (ΙΙ) complex in presence of erythromycin where: a) Solvent front b) Zn (ΙΙ) 0.0025% c) Cetirizine hydrochloride internal standard (15 μg/ml). d) Ebastine - Zn (ΙΙ) complex; (EBS = 4 μg/ml) e) Erythromycin (20 μg/ml) B. Typical chromatogram showing EBS-Zn (ΙΙ) complex in presence of ketoconazole where: a) Solvent front b) Zn (ΙΙ) 0.0025% c) Cetirizine hydrochloride internal standard (15 μg/ml). d) Ebastine - Zn (ΙΙ) complex; (EBS = 4 μg/ml) e) Ketoconazole (20 μg/ml)