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  1. Analysis of folic acid (FA) is not an easy task because of its presence in lower concentrations, its lower stability under acidic conditions, and its sensitiveness against light and high temperature. The prese...

    Authors: Samy Emara, Tsutomu Masujima, Walaa Zarad, Maha Kamal and Ramzia EL-Bagary
    Citation: Chemistry Central Journal 2012 6:155
    Content type: Research article Published on:

  2. Jack bean urease (EC 3.5.1.5) is a metalloenzyme, which catalyzes the hydrolysis of urea to produce ammonia and carbon dioxide. The heavy metal ions are common inhibitors to control the rate of the enzymatic u...

    Authors: Nana Du, Mingming Chen, Zhaodi Liu, Liangquan Sheng, Huajie Xu and Shuisheng Chen
    Citation: Chemistry Central Journal 2012 6:154
    Content type: Research article Published on:

  3. Biotransformation of organic compounds by using microbial whole cells provides an efficient approach to obtain novel analogues which are often difficult to synthesize chemically. In this manuscript, we report ...

    Authors: Naik Tameen Khan, Marium Bibi, Sammer Yousuf, Izhar Husain Qureshi, Atta-ur-Rahman, Abdullah Mohammad Al-Majid, Muhammad Ahmed Mesaik, Ahmed Shukralla Khalid, Samina A Sattar, Atia-tul-Wahab and M Iqbal Choudhary
    Citation: Chemistry Central Journal 2012 6:153
    Content type: Research article Published on:

  4. Thromboxane A2 is derived from arachidonic acid through the action of cyclooxygenases and thromboxane synthase. It is mainly formed in blood platelets upon activation and plays an important role in aggregation. A...

    Authors: Taghreed Hirz, Ali Khalaf, Nehme El-Hachem, May F Mrad, Hassan Abdallah, Christophe Créminon, René Grée, Raghida Abou Merhi, Aïda Habib, Ali Hachem and Eva Hamade
    Citation: Chemistry Central Journal 2012 6:152
    Content type: Research article Published on:

  5. Enantioselective hydrogenation of ketones is a key reaction in organic chemistry. In the past, we have attempted to deal with some unsolved challenges in this arena by introducing chiral tridentate phosphine-d...

    Authors: José A Fuentes, Scott D Phillips and Matthew L Clarke
    Citation: Chemistry Central Journal 2012 6:151
    Content type: Preliminary communication Published on:

  6. Clematichinenoside AR is a promising lead compound for the treatment of rheumatoid arthritis. A systematic research for the related impurities in AR bulk samples is still lacking. For the safe use of this natu...

    Authors: Yang Zhou, Yue Guan, Ji Shi, Xiaolin Zhang, Lan Yao and Lifang Liu
    Citation: Chemistry Central Journal 2012 6:150
    Content type: Research article Published on:

  7. Microalgae have attracted major interest as a sustainable source for biodiesel production on commercial scale. This paper describes the screening of six microalgal species, Scenedesmus quadricauda, Scenedesmus ac...

    Authors: Syed Ghulam Musharraf, Muhammad Arif Ahmed, Noureen Zehra, Nurul Kabir, M Iqbal Choudhary and Atta-ur Rahman
    Citation: Chemistry Central Journal 2012 6:149
    Content type: Research article Published on:

  8. Human kallikrein-related peptidase 6 (KLK6) has been implicated in various types of cancer and in neurodegenerative and demyelinating diseases including multiple sclerosis. Further, anti-KLK6 antibodies attenu...

    Authors: Georgia Sotiropoulou, Georgios Pampalakis, Evangelia Prosnikli, Gregory P Evangelatos and Evangelia Livaniou
    Citation: Chemistry Central Journal 2012 6:148
    Content type: Research article Published on:

  9. Plants of the genus Elsholtzia (Lamiaceae) have a long history of medicinal use in folk. The phytochemical investigations revealed the presence of flavonoids, phenylpropanoids, terpenoids, and other compounds. Ab...

    Authors: Zhiqin Guo, Zizhen Liu, Xiaohong Wang, Weirui Liu, Rui Jiang, Ruiyang Cheng and Gaimei She
    Citation: Chemistry Central Journal 2012 6:147
    Content type: Review Published on:

  11. Ariadne’s house, located at the city center of ancient Pompeii, is of great archaeological value due to the fresco paintings decorating several rooms. In order to assess the risks for long-term conservation af...

    Authors: Paloma Merello, Fernando-Juan García-Diego and Manuel Zarzo
    Citation: Chemistry Central Journal 2012 6:145
    Content type: Research article Published on:

  12. Particle tracking passive microrheology relates recorded trajectories of microbeads, embedded in soft samples, to the local mechanical properties of the sample. The method requires intensive numerical data pro...

    Authors: Timo Maier and Tamás Haraszti
    Citation: Chemistry Central Journal 2012 6:144
    Content type: Software Published on:

  13. In the present study, chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction was rapidly evaluated by UPLC-QTOF-MS coupled with the MarkerLynx software. Two diff...

    Authors: Erxin Shang, Zhenhua Zhu, Li Liu, Yuping Tang and Jin-ao Duan
    Citation: Chemistry Central Journal 2012 6:143
    Content type: Research article Published on:

  14. A new method is developed to quantify molar equivalents of N-hydroxysuccinimide (NHS) esters of derivatives of monomethoxyl poly-(ethylene glycol) (mPEG) in their preparations with NHS acetate ester as the refere...

    Authors: Ang Gao, Xiaolan Yang, Chun Zhang, Gaobo Long, Jun Pu, Yonghua Yuan, Hongbo Liu, Yuanli Li and Fei Liao
    Citation: Chemistry Central Journal 2012 6:142
    Content type: Methodology Published on:

  15. Tumor, is one of the major reason for human death, due to its widespread occurrence. Betulinic acid derivatives have attracted considerable attention as cancer chemopreventive agents and also as cancer therape...

    Authors: Shengjie Yang, Na Liang, Hu Li, Wei Xue, Deyu Hu, Linhong Jin, Qi Zhao and Song Yang
    Citation: Chemistry Central Journal 2012 6:141
    Content type: Research article Published on:

  16. As a typical Chinese herbal medicine, rhizoma Cimicifugae (RC, 升麻 in Chinese) possesses various pharmacological effects involved in antioxidant activity. However, its antioxidant activity has not been reported so...

    Authors: Xican Li, Jing Lin, Yaoxiang Gao, Weijuan Han and Dongfeng Chen
    Citation: Chemistry Central Journal 2012 6:140
    Content type: Research article Published on:

  17. Src plays various roles in tumour progression, invasion, metastasis, angiogenesis and survival. It is one of the multiple targets of multi-target kinase inhibitors in clinical uses and trials for the treatment...

    Authors: Bucong Han, Xiaohua Ma, Ruiying Zhao, Jingxian Zhang, Xiaona Wei, Xianghui Liu, Xin Liu, Cunlong Zhang, Chunyan Tan, Yuyang Jiang and Yuzong Chen
    Citation: Chemistry Central Journal 2012 6:139
    Content type: Research article Published on:

  18. In vivo estimations of Pb particle bioavailability are costly and variable, because of the nature of animal assays. The most feasible alternative for increasing the number of investigations carried out on Pb part...

    Authors: Elise Deshommes, Robert Tardif, Marc Edwards, Sébastien Sauvé and Michèle Prévost
    Citation: Chemistry Central Journal 2012 6:138
    Content type: Review Published on:

  19. Pentacyclic triterpenes, mainly betulin and betulinic acid, are valuable anticancer agents found in the bark of birch tree. This study evaluates birch bark extracts for the active principles composition.

    Authors: Cristina A Dehelean, Codruţa Şoica, Ionuţ Ledeţi, Mihaela Aluaş, Istvan Zupko, Atena Gǎluşcan, Simona Cinta-Pinzaru and Melania Munteanu
    Citation: Chemistry Central Journal 2012 6:137
    Content type: Research article Published on:

  20. Structurally diverse aldehydes are successfully converted into acylals (1,1-diacetates) with acetic anhydride using NaHSO4-SiO2 as a mild, convenient and inexpensive catalyst under solvent-free conditions. The no...

    Authors: Ravi Kumar Kannasani, V V Satyanarayana Peruri and Srinivasa Reddy Battula
    Citation: Chemistry Central Journal 2012 6:136
    Content type: Methodology Published on:

  22. Response surface methodology by Box–Behnken design employing the multivariate approach enables substantial improvement in the method development using fewer experiments, without wastage of large volumes of org...

    Authors: Tanveer A Wani, Ajaz Ahmad, Seema Zargar, Nasr Y Khalil and Ibrahim A Darwish
    Citation: Chemistry Central Journal 2012 6:134
    Content type: Research article Published on:

  24. Phosphorus-containing high performance polymers have aroused wide interest, mainly due to good mechanical properties and their excellent fire resistance. The flexibility of synthetic polyphosphoesters allows t...

    Authors: Smaranda Iliescu, Leire Zubizarreta, Nicoleta Plesu, Lavinia Macarie, Adriana Popa and Gheorghe Ilia
    Citation: Chemistry Central Journal 2012 6:132
    Content type: Research article Published on:

  25. Microbial activity is a primary cause of deterioration in many foods and is often responsible for reduced quality and safety. Food-borne illnesses associated with E. coli O157:H7, S. aureus, S. enteritidis and L....

    Authors: Saroat Rawdkuen, Phunsiri Suthiluk, Damrongpol Kamhangwong and Soottawat Benjakul
    Citation: Chemistry Central Journal 2012 6:131
    Content type: Research article Published on:

  26. The serious impact effects of persistent organic pollutants such as organochlorine pesticides, especially dichlorodiphenyltrichloroethane family (DDTs) and hexachlorocyclohexane isomers (HCHs) have been causin...

    Authors: Naghmeh Saadati, Md Pauzi Abdullah, Zuriati Zakaria, Majid Rezayi and Nader Hosseinizare
    Citation: Chemistry Central Journal 2012 6:130
    Content type: Research article Published on:

  27. Recently, various metallocenes were synthesized and analyzed by biological activity point of view (such as antiproliferative properties): ruthenocenes, cobaltoceniums, titanocenes, zirconocenes, vanadocenes, n...

    Authors: Adrian Riviş, Nicoleta G Hădărugă, Zeno Gârban and Daniel I Hădărugă
    Citation: Chemistry Central Journal 2012 6:129
    Content type: Research article Published on:

  28. Many efforts have been recently devoted to design, investigate and synthesize biocompatible, biodegradable polymers for applications in medicine for either the fabrication of biodegradable devices or as drug d...

    Authors: Ayman El-Faham, Hammed HAM Hassan and Sherine N Khattab
    Citation: Chemistry Central Journal 2012 6:128
    Content type: Research article Published on:

  29. Ni2O3- γ-Fe2O3 composite nanoparticles coated with a layer of 2FeCl3·5H2O can be prepared by co-precipitation and processing in FeCl2 solution. Using vibrating sample magnetometer (VSM), X-ray diffraction (XRD), ...

    Authors: Yueqiang Lin, Jian Li, Lihua Lin, Xiaodong Liu, Longlong Chen and Jun Fu
    Citation: Chemistry Central Journal 2012 6:127
    Content type: Research article Published on:

  31. For therapeutic monitoring and pharmacokinetic studies of lenalidomide (LND), the potent drug for treatment of multiple myeloma (MM), a specific antibody was required for the development of a sensitive immunoa...

    Authors: Ibrahim A Darwish, Nourh Z Alzoman, Reem M Abuhejail and Tilal E El-Samani
    Citation: Chemistry Central Journal 2012 6:125
    Content type: Research article Published on:

  33. Extensive research has been performed worldwide and important evidences were collected to show the immense potential of plants used in various traditional therapeutic systems. The aim of this work is to invest...

    Authors: Angela Caunii, George Pribac, Ioana Grozea, Dorin Gaitin and Ionel Samfira
    Citation: Chemistry Central Journal 2012 6:123
    Content type: Research article Published on:

  34. The study aims to determine the nutritional value of hemp seed expressed by the oil content and by the concentration of metals (Ca, Mg, K, Fe, Mn, Zn and Cd), for five varieties of monoecious and dioecious hem...

    Authors: Marcela Mihoc, Georgeta Pop, Ersilia Alexa and Isidora Radulov
    Citation: Chemistry Central Journal 2012 6:122
    Content type: Research article Published on:

  36. Electrospray tandem mass spectrometry approach is widely used for the rapid characterization of natural products. This paper describes the gas-phased ESI-MS/MS fragmentation of abietane-type diterpenoids and t...

    Authors: Syed Ghulam Musharraf, Madiha Goher, Amjad Hussain and M Iqbal Choudhary
    Citation: Chemistry Central Journal 2012 6:120
    Content type: Research article Published on:

  37. The metals bioavailability in soils is commonly assessed by chemical extractions; however a generally accepted method is not yet established. In this study, the effectiveness of Diffusive Gradients in Thin-fil...

    Authors: Marin Senila, Erika Andrea Levei and Lacrimioara Ramona Senila
    Citation: Chemistry Central Journal 2012 6:119
    Content type: Research article Published on:

  38. Lenalidomide (LND) is a potent novel thalidomide analog which demonstrated remarkable clinical activity in treatment of multiple myeloma disease via a multiple-pathways mechanism. The strong evidences-based cl...

    Authors: Ibrahim A Darwish, Nasr Y Khalil, Ahmed H Bakheit and Nourh Z Alzoman
    Citation: Chemistry Central Journal 2012 6:118
    Content type: Research article Published on:

  39. The biological functions of natural biopolymers from plant sources depend on their chemical composition and molecular structure. In addition, the extraction and further processing conditions significantly infl...

    Authors: Bahareh Tabatabaee Amid, Hamed Mirhosseini and Sanja Kostadinović
    Citation: Chemistry Central Journal 2012 6:117
    Content type: Research article Published on:

  40. “Dragon’s Blood” (DB) has long been used as an ethnomedicine in China to invigorate blood circulation for the treatment of traumatic injuries, blood stasis and pain. To comprehensively assess the quality of DB...

    Authors: Tao Yi, Yina Tang, Jianye Zhang, Zhongzhen Zhao, Zhijun Yang and Hubiao Chen
    Citation: Chemistry Central Journal 2012 6:116
    Content type: Research article Published on:

  41. Saccharide materials have been used for centuries as binding media, to paint, write and illuminate manuscripts and to apply metallic leaf decorations. Although the technical literature often reports on the use...

    Authors: Anna Lluveras-Tenorio, Joy Mazurek, Annalaura Restivo, Maria Perla Colombini and Ilaria Bonaduce
    Citation: Chemistry Central Journal 2012 6:115
    Content type: Research article Published on:

  42. Atorvastatin calcium (ATC), an anti-lipid biopharmaceutical class II drug, is widely prescribed as a cholesterol-lowering agent and is presently the world’s best-selling medicine. A large number of crystalline...

    Authors: Renu Chadha, Astha Kuhad, Poonam Arora and Shyam Kishor
    Citation: Chemistry Central Journal 2012 6:114
    Content type: Research article Published on:

  43. The work aims at improving photocatalytic activity of titania under Vis light irradiation using modification by Sn ions and an original, simple synthesis method. Tin-doped titania catalysts were prepared by th...

    Authors: Václav Štengl, Tomáš Matys Grygar, Jiří Henych and Martin Kormunda
    Citation: Chemistry Central Journal 2012 6:113
    Content type: Research article Published on:

  44. Despite considerable global investigation over several decades, the roles of vitamin D in health and disease development remains convoluted. One recognised issue is the difficulty of accurately measuring the a...

    Authors: Iltaf Shah, Andrea Petroczi and Declan P Naughton
    Citation: Chemistry Central Journal 2012 6:112
    Content type: Research article Published on:

  45. The design and applications of antimicrobial polymers is a growing field. Antimicrobial polymers can help to solve the problems associated with the use of conventional antimicrobial agents. Polymers with activ...

    Authors: Abdullah Alamri, Mohamed H El-Newehy and Salem S Al-Deyab
    Citation: Chemistry Central Journal 2012 6:111
    Content type: Research article Published on:

  46. In serious consideration of the worldwide environmental issues associated with the extensive use of the textile dyes and effluents generated thereof, the scientists across the world are in search for potential...

    Authors: Muhammad Asgher, Shagufta Kamal and Hafiz Muhammad Nasir Iqbal
    Citation: Chemistry Central Journal 2012 6:110
    Content type: Research article Published on:

  47. Biotransformation by using microbial and plant cell cultures has been applied effectively for the production of fine chemicals on large scale. Inspired by the wealth of literature available on the biotransform...

    Authors: Salman Zafar, Sammer Yousuf, Hammad A Kayani, Saifullah Saifullah, Saifullah Khan, Abdullah M Al-Majid and M Iqbal Choudhary
    Citation: Chemistry Central Journal 2012 6:109
    Content type: Research article Published on:

  48. Litchi (Litchi chinensis Sonn.) pericarp is a major byproduct which contains a significant amount of polyphenol. This study was designed to biotransformation litchi pericarp extract (LPE) by Aspergillus awamori t...

    Authors: Sen Lin, Bao Yang, Feng Chen, Guoxiang Jiang, Qing Li, Xuewu Duan and Yueming Jiang
    Citation: Chemistry Central Journal 2012 6:108
    Content type: Research article Published on:

  50. The new combination of moxifloxacin HCl and cefixime trihydrate is approved for the treatment of lower respiratory tract infections in adults. At initial formulation development and screening stage a fast and ...

    Authors: Mahesh Attimarad, Bander E Al-Dhubiab, Ibrahim A Alhaider, Anroop B Nair, Sree Harsha N and Mueen Ahmed K
    Citation: Chemistry Central Journal 2012 6:105
    Content type: Research article Published on:
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