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  1. Recently, an increased interest in the identification of valuable possibilities for preserving the antioxidant properties of products obtained by thermal processing of fruits rich in bioactive compounds can be...

    Authors: Mariana-Atena Poiana, Ersilia Alexa and Constantin Mateescu
    Citation: Chemistry Central Journal 2012 6:4
  2. The virtual screening (VS) of lead compounds using molecular docking and pharmacophore detection is now an important tool in drug discovery. VS tasks typically require a combination of several software tools a...

    Authors: Yin Xue Sun, Yan Xin Huang, Feng Li Li, Hong Yan Wang, Cong Fan, Yong Li Bao, Lu Guo Sun, Zhi Qiang Ma, Jun Kong and Yu Xin Li
    Citation: Chemistry Central Journal 2012 6:2
  3. A novel 96-microwell-based spectrophotometric assay has been developed and validated for determination of olmesartan medoxomil (OLM) in tablets. The formation of a colored charge-transfer (CT) complex between ...

    Authors: Ibrahim A Darwish, Tanveer A Wani, Nasr Y Khalil, Abdul-Aziz Al-Shaikh and Najm Al-Morshadi
    Citation: Chemistry Central Journal 2012 6:1
  4. In order to develop colloidal drug carriers with desired properties, it is important to determine physico-chemical characteristics of these systems. Bile salt mixed micelles are extensively studied as novel dr...

    Authors: Dejan M Ćirin, Mihalj M Poša and Veljko S Krstonošić
    Citation: Chemistry Central Journal 2011 5:89
  5. Recent studies showed that moderate consumption of red or white wines increased the chances of breast cancer, while similar consumption of red wines, rich in trans-resveratrol (trans-R), decreased the rate of pro...

    Authors: Natalia YU Anisimova, Mikhail V Kiselevsky, Andrey V Sosnov, Sergey V Sadovnikov, Ivan N Stankov and Andrei A Gakh
    Citation: Chemistry Central Journal 2011 5:88
  6. Amino acids are safe molecules with variable efficacy against ulceration. Considering the good antioxidant potential of N-aroyl- N, N'-dicyclohexyl urea and antiulcer activities of amino acids, a series of amino ...

    Authors: Bharat Bhusan Subudhi and Shakti Prasanna Sahoo
    Citation: Chemistry Central Journal 2011 5:86
  7. Three simple and rapid spectrophotometric methods were developed for detection and trace determination of benzophenone (the main impurity) in phenytoin bulk powder and pharmaceutical formulations. The first me...

    Authors: Mohamed Ibrahim Walash, Mohamed Salem Rizk, Zeinab Awad Sheribah and Mohamed Mansour Salim
    Citation: Chemistry Central Journal 2011 5:85
  8. Acetamidines are starting materials for synthesizing many chemical substances, such as imidazoles, pyrimidines and triazines, which are further used for biochemically active compounds as well as energetic mate...

    Authors: Zdeněk Jalový, Robert Matyáš, Jan Ottis, Aleš Růžička, Petr Šimůnek and Miroslav Polášek
    Citation: Chemistry Central Journal 2011 5:84
  9. Fibroblasts derived from the progeroid Werner syndrome show reduced replicative lifespan and a "stressed" morphology, both alleviated using the MAP kinase inhibitor SB203580. However, interpretation of these d...

    Authors: Terence Davis, Matthew C Dix, Michal J Rokicki, Amy JC Brook, Caroline S Widdowson, David Kipling and Mark C Bagley
    Citation: Chemistry Central Journal 2011 5:83
  10. SmCl3 (20 mol%) has been used as an efficient catalyst for reaction between aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione at 120°C to give 1,8-dioxo-octahydroxanthene derivatives in high yield. The sam...

    Authors: Andivelu Ilangovan, Subramani Malayappasamy, Samraj Muralidharan and Sundaram Maruthamuthu
    Citation: Chemistry Central Journal 2011 5:81
  11. We report the first synthesis of a cobalt Cp diene complex wherein the diene is derived by microbial dearomatising dihydroxylation of an aromatic ring. The complex has been characterised crystallographically a...

    Authors: Dominic van der Waals, Thomas Pugh, Monika Ali Khan, Alan JW Stewart, Andrew L Johnson and Simon E Lewis
    Citation: Chemistry Central Journal 2011 5:80
  12. Extraction of oil from the seed of Blighia unijugata gave a yield of 50.82 ± 1.20% using hexane in a soxhlet extractor. The iodine and saponification values were 67.60 ± 0.80 g iodine/100 g and 239.20 ± 1.00 mg K...

    Authors: Adewale Adewuyi, Rotimi A Oderinde, BVSK Rao, RBN Prasad and M Nalla
    Citation: Chemistry Central Journal 2011 5:79
  13. A simple reversed phase high performance liquid chromatographic method with diode array detector (HPLC-DAD) has been developed and subsequently validated for the determination of fexofenadine hydrochloride (FE...

    Authors: Hadir M Maher, Maha A Sultan and Ileana V Olah
    Citation: Chemistry Central Journal 2011 5:76
  14. Synthetic multi-substituted hydroxyapatite nano powders containing silicon and or carbonate prepared by a wet chemical method. The process parameters are set up to allow the simultaneous substitution of carbon...

    Authors: Doreya Mohamed Ibrahim, Amany A Mostafa and Sara Ibrahim Korowash
    Citation: Chemistry Central Journal 2011 5:74
  15. Chemical investigations of the 70% alcohol extract of Oxytropis myriophylla (Pall.) DC. (Leguminosae) have afforded the new natural product neohesperidin dihydrochalcone (1) and the known phloretin-4'-O-β-D-gluco...

    Authors: Gaimei She, Si Wang and Bin Liu
    Citation: Chemistry Central Journal 2011 5:71
  16. A rapid, simple and sensitive synchronous specrtofluorimetric method has been developed for the simultaneous analysis of binary mixture of metoprolol (MTP) and felodipine (FDP). The method is based upon measur...

    Authors: Mohamed I Walash, Fathallah F Belal, Nahed M El-Enany and Mahmoud H El-Maghrabey
    Citation: Chemistry Central Journal 2011 5:70
  17. One of the goals of the 2011 International Year of Chemistry is to celebrate the contributions of women to science. A question that has been frequently asked in this regard is... Why is it necessary to highlight ...

    Authors: Sharon L Haynie, Amber S Hinkle, Nancy L Jones, Cheryl A Martin, Paula J Olsiewski and Mary F Roberts
    Citation: Chemistry Central Journal 2011 5:69
  18. Fatty acids (FAs) are important as raw materials for the biotechnology industry. Existing methods of FAs production are based on chemical methods. In this study potassium hydroxide (KOH)-catalyzed reactions we...

    Authors: Jumat Salimon, Bashar Mudhaffar Abdullah and Nadia Salih
    Citation: Chemistry Central Journal 2011 5:67
  19. A new spectrophotometric method is developed for the determination of phenylpropanolamine HCl (PPA), ephedrine HCl (EPH) and pseudoephedrine HCl (PSE) in pharmaceutical preparations and spiked human urine. The...

    Authors: Mohamed I Walash, Nahed M El-Enany and Samar Saad
    Citation: Chemistry Central Journal 2011 5:65
  20. The aim of this study is to measure the levels of heavy metals (Fe, Mn, Zn, Cu, Ni, Cd and Pb) found in common vegetables (parsley, carrot, onion, lettuce, cucumber and green beans) grown in contaminated minin...

    Authors: Monica Harmanescu, Liana Maria Alda, Despina Maria Bordean, Ioan Gogoasa and Iosif Gergen
    Citation: Chemistry Central Journal 2011 5:64
  21. Owing to frequent administration of a wide range of pharmaceutical products, various environmental waters have been found to be contaminated with pharmacologically active substances. For example, stanozolol, a...

    Authors: Nawed IK Deshmukh, James Barker, Andrea Petroczi and Declan P Naughton
    Citation: Chemistry Central Journal 2011 5:63
  22. Considering the pharmaceutical importance of hydantoins, a set of 25 derivatives of phenytoin, nirvanol and 5-methyl-5-phenylhydantoin, the lipophilicities of which were gradually increased by the introduction...

    Authors: Nemanja Trišović, Nataša Valentić and Gordana Ušćumlić
    Citation: Chemistry Central Journal 2011 5:62
  23. Sertraline is a well known antidepressant drug which belongs to a class called selective serotonin reuptake inhibitor. Most published methods do not enable studying the stability of this drug in different stre...

    Authors: Mohamed I Walash, Fathallah F Belal, Nahed M El-Enany and Heba Elmansi
    Citation: Chemistry Central Journal 2011 5:61
  24. A simple, sensitive and rapid spectrophotometric method was developed and validated for the determination of two skeletal muscle relaxants namely, tizanidine hydrochloride (I) and orphenadrine citrate (II) in ...

    Authors: Mohamed I Walash, Fathalla F Belal, Manal I Eid and Samah Abo El Abass Mohamed
    Citation: Chemistry Central Journal 2011 5:60
  25. In silico models have prompted considerable interest and debate because of their potential value in predicting the properties of chemical substances for regulatory purposes. The European REACH legislation promote...

    Authors: Emilio Benfenati, Rodolfo Gonella Diaza, Antonio Cassano, Simon Pardoe, Giuseppina Gini, Claire Mays, Ralf Knauf and Ludger Benighaus
    Citation: Chemistry Central Journal 2011 5:58
  26. The formation of a colored charge-transfer (CT) complex between atorvastatin calcium (ATR-Ca) as a n-electron donor and 2, 3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as a π-electron acceptor was investigate...

    Authors: Tanveer A Wani, Nasr Y Khalil, Hamdy M Abdel-Rahman and Ibrahim A Darwish
    Citation: Chemistry Central Journal 2011 5:57
  27. Sertraline is primarily used to treat major depression in adult outpatients as well as obsessive-compulsive, panic and social anxiety disorders in both adults and children. A survey of the literature reveals t...

    Authors: Nahed M El-Enany, Amina Abdelal and Fathalla Belal
    Citation: Chemistry Central Journal 2011 5:56
  28. Novel mono N-alkyl quaternary ammonium salts (3a-f) were prepared using the Menschutkin reaction from the cage adamanzane type aminal 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane (TATU) and alkyl iodides, such as...

    Authors: Augusto Rivera, John Sadat-Bernal, Jaime Ríos-Motta, Michal Dušek and Lukáš Palatinus
    Citation: Chemistry Central Journal 2011 5:55
  29. The low-temperature heat capacities of nickel titanate (NiTiO3), cobalt titanate (CoTiO3), and cobalt carbonate (CoCO3) were measured between 2 and 300 K, and thermochemical functions were derived from the result...

    Authors: Stephan Klemme, Wilfried Hermes, Mathias Eul, Clazina H Wijbrans, Arno Rohrbach and Rainer Pöttgen
    Citation: Chemistry Central Journal 2011 5:54
  30. This paper reports a systematic study of the level of flavan-3-ol monomers during typical processing steps as cacao beans are dried, fermented and roasted and the results of Dutch-processing. Methods have been...

    Authors: W Jeffrey Hurst, Susann H Krake, Stephen C Bergmeier, Mark J Payne, Kenneth B Miller and David A Stuart
    Citation: Chemistry Central Journal 2011 5:53
  31. The natural polyether ionophorous antibiotics are used for the treatment of coccidiosis in poultry and ruminants. They are effective agents against infections caused by Gram-positive microorganisms. On the oth...

    Authors: Juliana Ivanova, Ivayla N Pantcheva, Mariana Mitewa, Svetlana Simova, Makoto Tanabe and Kohtaro Osakada
    Citation: Chemistry Central Journal 2011 5:52
  32. Cytosine is a biologically important compound owing to its natural occurrence as a component of nucleic acids. Cytosine plays a crucial role in DNA/RNA base pairing, through several hydrogen-bonding patterns, ...

    Authors: Gustavo Portalone
    Citation: Chemistry Central Journal 2011 5:51
  33. There have been many recent developments of in vitro cigarette smoke systems closely replicating in vivo exposures. The Borgwaldt RM20S smoking machine (RM20S) enables the serial dilution and delivery of cigarett...

    Authors: Jason Adamson, David Azzopardi, Graham Errington, Colin Dickens, John McAughey and Marianna D Gaça
    Citation: Chemistry Central Journal 2011 5:50
  34. Due to the vast importance of peptides in biological processes, there is an escalating need for synthetic peptides to be used in a wide variety of applications. However, the consumption of organic solvent is e...

    Authors: Keiko Hojo, Asaki Hara, Hiroyuki Kitai, Mare Onishi, Hideki Ichikawa, Yoshinobu Fukumori and Koichi Kawasaki
    Citation: Chemistry Central Journal 2011 5:49
  35. The AgBr loaded TiO2 catalyst was prepared by a feasible approach with AgBr and tetraisopropyl orthotitanate and characterized by BET surface area measurement, diffuse reflectance spectra (DRS), scanning electron...

    Authors: Rengasamy Velmurugan, Bojja Sreedhar and Meenakshisundaram Swaminathan
    Citation: Chemistry Central Journal 2011 5:46
  36. The spiro- indole-pyrrolidine ring system is a frequently encountered structural motif in many biologically important and pharmacologically relevant alkaloids. The derivatives of spirooxindole ring systems are...

    Authors: Jeyaperumal Kalyana Sundar, Stephen Michael Rajesh, Jeyaraman Sivamani, Subbu Perumal and Subramanian Natarajan
    Citation: Chemistry Central Journal 2011 5:45

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