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Organic Chemistry

Edited by Vassya Bankova​​​​​​​

Scope: This section publishes articles in all areas of organic chemistry including organic synthesis, bioorganic chemistry, physical organic chemistry, stereochemistry, structure-activity relationships, synthetic methods, organometallic chemistry, and natural product chemistry.

  1. Eleven new tetrahydrobenzo[b]pyran derivatives were synthesized via a three component reaction of different aromatic aldehydes, methyl cyanoacetate and 1,3-cyclohexadione, with water as solvent under catalyst-...

    Authors: Mandlenkosi Robert Khumalo, Surya Narayana Maddila, Suresh Maddila and Sreekantha B. Jonnalagadda

    Citation: BMC Chemistry 2019 13:132

    Content type: Research article

    Published on:

  2. The side reactions of dehalogenation or C–N coupling tend to occur when halogenated aromatic amines are prepared by catalytic hydrogenation reduction of halogenated aromatic nitro compounds. In this paper, we ...

    Authors: Haichang Guo, Renhua Zheng, Huajiang Jiang, Zhenyuan Xu and Aibao Xia

    Citation: BMC Chemistry 2019 13:130

    Content type: Research article

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  3. Crosslinked sulfonated polyacrylamide (Cross-PAA-SO3H) attached to nano-Fe3O4 as a superior catalyst has been used for the synthesis of 3-alkyl-4-phenyl-1,3-thiazole-2(3H)-thione derivatives through a three-compo...

    Authors: Hossein Shahbazi-Alavi, Sheida Khojasteh-Khosro, Javad Safaei-Ghomi and Maryam Tavazo

    Citation: BMC Chemistry 2019 13:120

    Content type: Research article

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  4. The synthesized Fe3O4@l-arginine showed strong catalytic performance in the one-pot synthesis of spiropyranopyrazoles via the reactions of hydrazines, β-keto esters, isatins, and malononitrile or ethyl cyanoaceta...

    Authors: Mohammad Ali Ghasemzadeh, Boshra Mirhosseini-Eshkevari and Mohammad Hossein Abdollahi-Basir

    Citation: BMC Chemistry 2019 13:119

    Content type: Research article

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  5. Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4,5-dihydro-1H-pyrazole-1-carbothioamides 3a,b (obtained from the reaction of ...

    Authors: Abdelwahed R. Sayed, Sobhi M. Gomha, Fathy M. Abdelrazek, Mohamed S. Farghaly, Shaimaa A. Hassan and Peter Metz

    Citation: BMC Chemistry 2019 13:116

    Content type: Research article

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  7. Cu2O supported on peanut shell (Cu2O@PS) was prepared by the reaction of copper acetate and peanut shell powder as a naturally available biopolymer support. The prepared catalyst was used as an efficient and reus...

    Authors: Zahra Dolatkhah, Abolfazl Mohammadkhani, Shahrzad Javanshir and Ayoob Bazgir

    Citation: BMC Chemistry 2019 13:97

    Content type: Research article

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  8. Sulfonamide derivatives are of great attention due to their wide spectrum of biological activities. Sulfonamides conjugated with acetamide fragments exhibit antimicrobial and anticancer activities. The inhibit...

    Authors: Essam M. Hussein, Munirah M. Al-Rooqi, Shimaa M. Abd El-Galil and Saleh A. Ahmed

    Citation: BMC Chemistry 2019 13:91

    Content type: Research article

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  9. Organic compounds that contain nitrogen are very important intermediates in pharmaceutical and chemical industry. Hydroamination is the reaction that can form C–N bond with high atom economy. The research progres...

    Authors: Jingpei Huo, Guozhang He, Weilan Chen, Xiaohong Hu, Qianjun Deng and Dongchu Chen

    Citation: BMC Chemistry 2019 13:89

    Content type: Review

    Published on:

  10. The title compounds, 2-azaspiro[4.5]deca-1-one, C9H15NO, (1a), cis-8-methyl-2-azaspiro[4.5]deca-1-one, C10H17NO, (1b), and trans-8-methyl-2-azaspiro[4.5]deca-1-one, C10H17NO, (1c), were synthesized from benzoic a...

    Authors: Tobias Krueger, Alexandra Kelling, Torsten Linker and Uwe Schilde

    Citation: BMC Chemistry 2019 13:69

    Content type: Research article

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  11. Following publication of the original article [1], the authors reported an error in Schemes 1 and 2 and repeated line in subsection “Bis(ligand) nickel(II) chelate (NiL12)”.

    Authors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke and Kuo-Hsiung Lee

    Citation: BMC Chemistry 2019 13:63

    Content type: Correction

    Published on:

    The original article was published in BMC Chemistry 2019 13:51

  12. The general approach to the synthesis of metal complexes begins with ligand synthesis, followed by ligand reaction with metal salts to afford organometallic complexes. Our research group first reported a one-p...

    Authors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke and Kuo-Hsiung Lee

    Citation: BMC Chemistry 2019 13:51

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Chemistry 2019 13:63

  13. Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores w...

    Authors: Abdou O. Abdelhamid, Ibrahim E. El Sayed, Yasser H. Zaki, Ahmed M. Hussein, Mangoud M. Mangoud and Mona A. Hosny

    Citation: BMC Chemistry 2019 13:48

    Content type: Research article

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  14. The present study reveals the robust and facile methodology for the synthesis of massively selective dispiro-3-phenylpyrrolothiazole hybrids via one-pot 1,3-dipolar cycloaddition reaction by environmentally su...

    Authors: Govindasami Periyasami, Karuppiah Ponmurugan, Natarajan Arumugam, Raju Sureshkumar, Mostafizur Rahaman, Durairaju Periyan, Naif Abdullah Al-Dhabi, Shaykha Alzahly and Ali Aldalbahi

    Citation: BMC Chemistry 2019 13:42

    Content type: Research article

    Published on:

  15. A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, ...

    Authors: M. Mujahid Alam, Ahmed T. Mubarak, Mohammed A. Assiri, S. Merajuddin Ahmed and Ahmed M. Fouda

    Citation: BMC Chemistry 2019 13:40

    Content type: Research article

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  16. A convenient approach for (1E,3E)-1,4-diarylbuta-1,3-dienes via intermolecular Heck reaction of olefins and β-bromostyrenes promoted by μ-OMs palladium–dimer complex has been successfully developed. The products ...

    Authors: Xueliang Zhou, Yuan Zhou, Qiang Zhu, Huimin Chen, Nan Wu, Xiangru Wen and Zhou Xu

    Citation: BMC Chemistry 2019 13:39

    Content type: Research article

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  17. Thiazole is a core structural motif presents in a wide range of natural products. Thiazole derivatives also have a wide range of medicinal and biological properties.

    Authors: Mona A. Hosny, Yasser H. Zaki, Wafaa A. Mokbel and Abdou O. Abdelhamid

    Citation: BMC Chemistry 2019 13:37

    Content type: Research article

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  18. 4-Thiazolidinone ring is reported to have almost all types of biological activities. Also, it present in many marketed drugs.

    Authors: Yahia N. Mabkhot, Mohammed M. Alharbi, Salim. S. Al-Showiman, Saied M. Soliman, Nabila A. Kheder, Wolfgang Frey, Abdulrhman Asayari, Abdullatif Bin Muhsinah and H. Algarni

    Citation: BMC Chemistry 2019 13:35

    Content type: Research article

    Published on:

  19. penta-1,4-diene-3-one oxime ether and quinazolin-4(3H)-one derivatives possess favorable agricultural activities. Aiming to discover novel molecules with highly-efficient agricultural activities, a series of pent...

    Authors: Lijuan Chen, Xiaobin Wang, Xu Tang, Rongjiao Xia, Tao Guo, Cheng Zhang, Xiangyang Li and Wei Xue

    Citation: BMC Chemistry 2019 13:34

    Content type: Research article

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  21. Indole based thiadiazole derivatives (1–22) have synthesized, characterized by NMR and HREI-MS and evaluated for β-Glucuronidase inhibition. All compounds showed outstanding β-glucuronidase activity with IC50 val...

    Authors: Noor Barak Almandil, Muhammad Taha, Mohammed Gollapalli, Fazal Rahim, Mohamed Ibrahim, Ashik Mosaddik and El Hassane Anouar

    Citation: BMC Chemistry 2019 13:14

    Content type: Research article

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  22. Dihydrofolate reductase (DHFR) is an important target for antimetabolite class of antimicrobials because it participates in purine synthesis. 2-mercaptobenzimidazole (2MBI) has similar structural features as p...

    Authors: Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:12

    Content type: Research article

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  23. This work deals with the synthesis and characterization of the novel 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihydro-pyrimidine-4,6(1H,5H)-dione π-bridge (D–A–D) donor–acceptor–donor compound. I...

    Authors: Mezna Saleh Altowyan, Assem Barakat, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, Abdelkader Zarrouk and Ismail Warad

    Citation: BMC Chemistry 2019 13:11

    Content type: Research article

    Published on:

  24. The resinous exudates from Escallonia illinita by products was characterized by FT-IR, NMR and HRMS. Six compounds were isolated and identified as follows: 1,5-diphenylpent-1-en-3-one (1), 4-(5-hydroxy-3,7-dimeth...

    Authors: Iván Montenegro, Elizabeth Sánchez, Enrique Werner, Patricio Godoy, Yusser Olguín, Nelson Caro, Nicole Ehrenfeld and Alejandro Madrid

    Citation: BMC Chemistry 2019 13:1

    Content type: Research article

    Published on:

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