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Organic Chemistry

Edited by Vassya Bankova​​​​​​​

Scope: This section publishes articles in all areas of organic chemistry including organic synthesis, bioorganic chemistry, physical organic chemistry, stereochemistry, structure-activity relationships, synthetic methods, organometallic chemistry, and natural product chemistry.

  1. Content type: Research article

    Sulfonamide derivatives are of great attention due to their wide spectrum of biological activities. Sulfonamides conjugated with acetamide fragments exhibit antimicrobial and anticancer activities. The inhibit...

    Authors: Essam M. Hussein, Munirah M. Al-Rooqi, Shimaa M. Abd El-Galil and Saleh A. Ahmed

    Citation: BMC Chemistry 2019 13:91

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  2. Content type: Review

    Organic compounds that contain nitrogen are very important intermediates in pharmaceutical and chemical industry. Hydroamination is the reaction that can form C–N bond with high atom economy. The research progres...

    Authors: Jingpei Huo, Guozhang He, Weilan Chen, Xiaohong Hu, Qianjun Deng and Dongchu Chen

    Citation: BMC Chemistry 2019 13:89

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  3. Content type: Research article

    The title compounds, 2-azaspiro[4.5]deca-1-one, C9H15NO, (1a), cis-8-methyl-2-azaspiro[4.5]deca-1-one, C10H17NO, (1b), and trans-8-methyl-2-azaspiro[4.5]deca-1-one, C10H17NO, (1c), were synthesized from benzoic a...

    Authors: Tobias Krueger, Alexandra Kelling, Torsten Linker and Uwe Schilde

    Citation: BMC Chemistry 2019 13:69

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  4. Content type: Correction

    Following publication of the original article [1], the authors reported an error in Schemes 1 and 2 and repeated line in subsection “Bis(ligand) nickel(II) chelate (NiL12)”.

    Authors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke and Kuo-Hsiung Lee

    Citation: BMC Chemistry 2019 13:63

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    The original article was published in BMC Chemistry 2019 13:51

  5. Content type: Research article

    The general approach to the synthesis of metal complexes begins with ligand synthesis, followed by ligand reaction with metal salts to afford organometallic complexes. Our research group first reported a one-p...

    Authors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke and Kuo-Hsiung Lee

    Citation: BMC Chemistry 2019 13:51

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    The Correction to this article has been published in BMC Chemistry 2019 13:63

  6. Content type: Research article

    Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores w...

    Authors: Abdou O. Abdelhamid, Ibrahim E. El Sayed, Yasser H. Zaki, Ahmed M. Hussein, Mangoud M. Mangoud and Mona A. Hosny

    Citation: BMC Chemistry 2019 13:48

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  7. Content type: Research article

    The present study reveals the robust and facile methodology for the synthesis of massively selective dispiro-3-phenylpyrrolothiazole hybrids via one-pot 1,3-dipolar cycloaddition reaction by environmentally su...

    Authors: Govindasami Periyasami, Karuppiah Ponmurugan, Natarajan Arumugam, Raju Sureshkumar, Mostafizur Rahaman, Durairaju Periyan, Naif Abdullah Al-Dhabi, Shaykha Alzahly and Ali Aldalbahi

    Citation: BMC Chemistry 2019 13:42

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  8. Content type: Research article

    A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, ...

    Authors: M. Mujahid Alam, Ahmed T. Mubarak, Mohammed A. Assiri, S. Merajuddin Ahmed and Ahmed M. Fouda

    Citation: BMC Chemistry 2019 13:40

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  9. Content type: Research article

    A convenient approach for (1E,3E)-1,4-diarylbuta-1,3-dienes via intermolecular Heck reaction of olefins and β-bromostyrenes promoted by μ-OMs palladium–dimer complex has been successfully developed. The products ...

    Authors: Xueliang Zhou, Yuan Zhou, Qiang Zhu, Huimin Chen, Nan Wu, Xiangru Wen and Zhou Xu

    Citation: BMC Chemistry 2019 13:39

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  10. Content type: Research article

    Thiazole is a core structural motif presents in a wide range of natural products. Thiazole derivatives also have a wide range of medicinal and biological properties.

    Authors: Mona A. Hosny, Yasser H. Zaki, Wafaa A. Mokbel and Abdou O. Abdelhamid

    Citation: BMC Chemistry 2019 13:37

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  11. Content type: Research article

    4-Thiazolidinone ring is reported to have almost all types of biological activities. Also, it present in many marketed drugs.

    Authors: Yahia N. Mabkhot, Mohammed M. Alharbi, Salim. S. Al-Showiman, Saied M. Soliman, Nabila A. Kheder, Wolfgang Frey, Abdulrhman Asayari, Abdullatif Bin Muhsinah and H. Algarni

    Citation: BMC Chemistry 2019 13:35

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  12. Content type: Research article

    penta-1,4-diene-3-one oxime ether and quinazolin-4(3H)-one derivatives possess favorable agricultural activities. Aiming to discover novel molecules with highly-efficient agricultural activities, a series of pent...

    Authors: Lijuan Chen, Xiaobin Wang, Xu Tang, Rongjiao Xia, Tao Guo, Cheng Zhang, Xiangyang Li and Wei Xue

    Citation: BMC Chemistry 2019 13:34

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  14. Content type: Research article

    Indole based thiadiazole derivatives (1–22) have synthesized, characterized by NMR and HREI-MS and evaluated for β-Glucuronidase inhibition. All compounds showed outstanding β-glucuronidase activity with IC50 val...

    Authors: Noor Barak Almandil, Muhammad Taha, Mohammed Gollapalli, Fazal Rahim, Mohamed Ibrahim, Ashik Mosaddik and El Hassane Anouar

    Citation: BMC Chemistry 2019 13:14

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  15. Content type: Research article

    Dihydrofolate reductase (DHFR) is an important target for antimetabolite class of antimicrobials because it participates in purine synthesis. 2-mercaptobenzimidazole (2MBI) has similar structural features as p...

    Authors: Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:12

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  16. Content type: Research article

    This work deals with the synthesis and characterization of the novel 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihydro-pyrimidine-4,6(1H,5H)-dione π-bridge (D–A–D) donor–acceptor–donor compound. I...

    Authors: Mezna Saleh Altowyan, Assem Barakat, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, Abdelkader Zarrouk and Ismail Warad

    Citation: BMC Chemistry 2019 13:11

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  17. Content type: Research article

    The resinous exudates from Escallonia illinita by products was characterized by FT-IR, NMR and HRMS. Six compounds were isolated and identified as follows: 1,5-diphenylpent-1-en-3-one (1), 4-(5-hydroxy-3,7-dimeth...

    Authors: Iván Montenegro, Elizabeth Sánchez, Enrique Werner, Patricio Godoy, Yusser Olguín, Nelson Caro, Nicole Ehrenfeld and Alejandro Madrid

    Citation: BMC Chemistry 2019 13:1

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