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Analytical Chemistry

​​​​Scope: This section publishes articles in all areas of analytical chemistry including spectroscopy, crystallography, chromatography, imaging, chemometrics, data processing, and electrochemistry.

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  1. Linifanib (ABT-869) is an orally active receptor tyrosine kinase inhibitor, which simultaneously inhibits vascular endothelial and platelet derived growth factor receptor. The aim of the present study was to d...

    Authors: Muzaffar Iqbal, Essam Ezzeldin, Tanveer A Wani and Nasr Y Khalil

    Citation: Chemistry Central Journal 2014 8:13

    Content type: Research article

    Published on:

  2. Paper based artworks are probably ones of the most difficult materials to restore, because of their complexity and fragile structure. Cleaning of paper artifacts, one of the process commonly carried out during...

    Authors: Claudia Mazzuca, Laura Micheli, Federico Marini, Marta Bevilacqua, Gianfranco Bocchinfuso, Giuseppe Palleschi and Antonio Palleschi

    Citation: Chemistry Central Journal 2014 8:10

    Content type: Research article

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  3. A simple, rapid, and accurate stability-indicating reverse phase liquid chromatographic method was developed and validated for the simultaneous determination of pheniramine maleate and naphazoline hydrochlorid...

    Authors: Taomin Huang, Nianzu Chen, Donglei Wang, Yonghua Lai and Zhijuan Cao

    Citation: Chemistry Central Journal 2014 8:7

    Content type: Research article

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  4. Yakuchinone A has a plethora of beneficial biological effects. However, the pharmacokinetic (PK) data of yakuchinone A still remain unknown so far. Furthermore, the quantification of yakuchinone A in biologica...

    Authors: Feng Chen, Hai-Long Li, Yin-Feng Tan, Wei-Wei Guan, Yong-Hui Li and Jun-Qing Zhang

    Citation: Chemistry Central Journal 2014 8:2

    Content type: Research article

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  5. 4-substituted methylidene oxindoles are pharmacologically important. Detailed analysis and comparison of all the interactions present in crystal structures is necessary to understand how these structures arise...

    Authors: Graham J Tizzard, Simon J Coles, Mark Edwards, Romanus Oforbike Onyeabo, Mark Allen and John Spencer

    Citation: Chemistry Central Journal 2013 7:182

    Content type: Research article

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  6. Drugs photostability plays two different opposite roles; a real advantage arises considering the longer expiration time of the drugs while the consequent persistence in the environment involves an obvious nega...

    Authors: Maria Pia Sammartino, Mauro Castrucci, Daniele Ruiu, Giovanni Visco and Luigi Campanella

    Citation: Chemistry Central Journal 2013 7:181

    Content type: Research article

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  7. Pouch moist snuff, as a form of oral smokeless tobacco products, is becoming increasingly popular in North America, Scandinavia (where it is known as Snus), South Asia and parts of Africa. User usually places ...

    Authors: Peng Li, Jie Zhang, Shi-Hao Sun, Jian-Ping Xie and Yong-Li Zong

    Citation: Chemistry Central Journal 2013 7:176

    Content type: Methodology

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  8. Clarithromycin (CLM) is a semi-synthetic macrolide antibiotic with a broad antibacterial spectrum. It has a potent activity against Myc. Pneumonia, Legionella Spp., H. Influenza, and Mor. Catarrhalis. It is also ...

    Authors: Ibrahim A Darwish, Mohammed A Alqarni and Tanveer A Wani

    Citation: Chemistry Central Journal 2013 7:172

    Content type: Research article

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  9. Rhubarb is an important Chinese medicinal herb with a long history of over 2000 years and has been commonly used as a laxative. It is the radix and rhizome of Rheum officinale Baill., R. palmatum L. and R. tangut...

    Authors: Zhe Wang, Pei Ma, Lijia Xu, Chunnian He, Yong Peng and Peigen Xiao

    Citation: Chemistry Central Journal 2013 7:170

    Content type: Research article

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  10. Aconitum is an indispensable entity of the traditional medicine therapy in Ayurveda and Traditional Chinese medicine (TCM), in spite of its known fatal toxicity characteristics. The prolonged use of this drug,...

    Authors: Yogini Jaiswal, Zhitao Liang, Peng Yong, Hubiao Chen and Zhongzhen Zhao

    Citation: Chemistry Central Journal 2013 7:169

    Content type: Research article

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  11. Shen-Fu decoction is a traditional Chinese medicine prescription with a 3:2 ratio of Radix Ginseng and Fuzi ( Radix Aconiti lateralis praeparata ). Ginsenosides and alkaloids are considered to be the main active ...

    Authors: Na Guo, Mingtao Liu, Dawei Yang, Ying Huang, Xiaohong Niu, Ruifan Wu, Ying Liu, Guizhi Ma and Deqiang Dou

    Citation: Chemistry Central Journal 2013 7:165

    Content type: Research article

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  12. Levofloxacin hemihydrate (LEV) and ambroxol HCl (AMB) are available for the treatment of upper and lower respiratory tract infections. A survey of the literature reveals that two reversed phase HPLC methods we...

    Authors: Fathalla F Belal, Mohie K Sharaf El-Din, Nahed M El-Enany and Samar Saad

    Citation: Chemistry Central Journal 2013 7:162

    Content type: Research article

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  13. A comparative study of the use of mean centering of ratio spectra and inverse least squares for the resolution of paracetamol, methylparaben, propylparaben, chlorpheniramine maleate and pseudoephedrine hydroch...

    Authors: Mahmoud Mohamed Issa, R’afat Mahmoud Nejem, Alaa Mohamed Abu Shanab and Nahed Talab Shaat

    Citation: Chemistry Central Journal 2013 7:152

    Content type: Research article

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  14. Debate about the health implications of using smokeless tobacco products (STPs) has prompted considerable interest in characterising their levels of toxic and carcinogenic components. In the present study seve...

    Authors: Kevin G McAdam, Arif Faizi, Harriet Kimpton, Andrew Porter and Brad Rodu

    Citation: Chemistry Central Journal 2013 7:151

    Content type: Research article

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  15. Stanozolol is a synthetic derivative of dihydrotestosterone (DHT), and one of the frequently detected anabolic steroids in doping analysis. The current work describes the development and validation of the stab...

    Authors: Syed Ghulam Musharraf, Qamar ul Arfeen, Wardah Mazhar and Nayab Kanwal

    Citation: Chemistry Central Journal 2013 7:142

    Content type: Research article

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  16. The compatibility study of active substances with excipients finds an important role in the domain of pharmaceutical research, being known the fact that final formulation is the one administered to the patient...

    Authors: Adriana Fuliaş, Ionuţ Ledeţi, Gabriela Vlase, Călin Popoiu, Alina Hegheş, Mihai Bilanin, Titus Vlase, Dorina Gheorgheosu, Marius Craina, Simona Ardelean, Dumitru Ferechide, Otilia Mărginean and Liana Moş

    Citation: Chemistry Central Journal 2013 7:140

    Content type: Research article

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  17. The dried fruits of Alpinia oxyphylla Miq have been widely used as an herbal medicine for the treatment of diarrhea and enuresis in China. Medicinal chemistry studies revealed that the tepenes, diphenylheptanes a...

    Authors: Yong-Hui Li, Feng Chen, Jun-fang Wang, Yong Wang, Jun-Qing Zhang and Tao Guo

    Citation: Chemistry Central Journal 2013 7:134

    Content type: Research article

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  18. Ciprofloxacin (CIP), moxifloxacin (MOX), norfloxacin (NOR) and ofloxacin (OFL), are the antibacterial synthetic drugs, belonging to the fluoroquinolones group. Fluoroquinolones are compounds susceptible to pho...

    Authors: Urszula Hubicka, Paweł Żmudzki, Przemysław Talik, Barbara Żuromska-Witek and Jan Krzek

    Citation: Chemistry Central Journal 2013 7:133

    Content type: Research article

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  19. The h index bibliometric indicator for evaluating scientists and scientific institutions plays an increasingly important role in evaluating contemporary scientific research, including chemistry.

    Authors: Rosaria Ciriminna and Mario Pagliaro

    Citation: Chemistry Central Journal 2013 7:132

    Content type: Commentary

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  20. The SuoQuan formulae containing Fructus Alpiniae Oxyphyllae has been used to combat the urinary incontinence symptoms including frequency, urgency and nocturia for hundreds of years in China. However, the chemica...

    Authors: Feng Chen, Hai-long Li, Yong-Hui Li, Yin-Feng Tan and Jun-Qing Zhang

    Citation: Chemistry Central Journal 2013 7:131

    Content type: Research article

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  21. For the development of properties in molecular crystals, such as electrical conductivities, magnetic properties, or non-linear optical properties, not only the electronic properties of molecules themselves mat...

    Authors: Behrooz Rezaei and Mehrnoosh Fazlollahi

    Citation: Chemistry Central Journal 2013 7:130

    Content type: Research article

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  22. At present, the study on the homogeneous-phase derivatization of cellulose in ionic liquid is mainly focused on its acetylation. To the best of our knowledge, there has been no such report on the preparation o...

    Authors: Run-Qiang Liu, Lian-yang Bai, Yi-Jun Zhang and Yu-Ping Zhang

    Citation: Chemistry Central Journal 2013 7:129

    Content type: Preliminary communication

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  23. The root of Fordia cauliflora Hemsl (FC) has long been used in southern China for the treatment of rheumatism, bruises, dementia in children, and valetudinarianism. However, sometimes it is mixed with other parts...

    Authors: Lanlan Fan, Yazhou Zhang, Renbin Huang, Shanding Qin, Tao Yi, Feng Xu, Yina Tang, Xiaosheng Qu, Hubiao Chen and Jianhua Miao

    Citation: Chemistry Central Journal 2013 7:126

    Content type: Research article

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  24. A novel optical sensor for the rapid and direct determination of permethrin preservatives in treated wood was designed. The optical sensor was fabricated from the immobilisation of 2,6-dichloro-p-benzoquinone-...

    Authors: Mohamad Nasir Mat Arip, Lee Yook Heng, Musa Ahmad and Siti Aishah Hasbullah

    Citation: Chemistry Central Journal 2013 7:122

    Content type: Research article

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  25. Rhodiola plants are used as a natural remedy in the western world and as a traditional herbal medicine in China, and are valued for their ability to enhance human resistance to stress or fatigue and to promote lo...

    Authors: Zhenli Liu, Yuanyan Liu, Chunsheng Liu, Zhiqian Song, Qing Li, Qinglin Zha, Cheng Lu, Chun Wang, Zhangchi Ning, Yuxin Zhang, Cheng Tian and Aiping Lu

    Citation: Chemistry Central Journal 2013 7:118

    Content type: Research article

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  26. Root of Ficus hirta (RFH) is widely consumed in China as a plant-derived popular food. However, contents of the active constituents of RFH are unknown, and the chemical as well as bioactive properties of RFH may ...

    Authors: Tao Yi, Qilei Chen, Xicheng He, Suiwai So, Yuenling Lo, Lanlan Fan, Jun Xu, Yina Tang, Jianye Zhang, Zhongzhen Zhao and Hubiao Chen

    Citation: Chemistry Central Journal 2013 7:115

    Content type: Research article

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  27. Copper is an essential trace element with a great importance in industry, environment and biological systems. The great advantage of ion-selective sensors in comparison with other proposed techniques is that t...

    Authors: Dana Vlascici, Iuliana Popa, Vlad A Chiriac, Gheorghe Fagadar-Cosma, Horia Popovici and Eugenia Fagadar-Cosma

    Citation: Chemistry Central Journal 2013 7:111

    Content type: Research article

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  28. A conventional gravimetry and electro-gravimetry study has been carried out for the precise and accurate purity determination of lead (Pb) in high purity lead stick and for preparation of reference standard. R...

    Authors: Nahar Singh, Niranjan Singh, S Swarupa Tripathy, Daya Soni, Khem Singh and Prabhat K Gupta

    Citation: Chemistry Central Journal 2013 7:108

    Content type: Research article

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  29. Polygoni Multiflori Caulis, the dried caulis of Polygonum multiflorum Thunb., is one of the commonly used traditional Chinese medicines having antioxidant, anti-obesity, anti-inflammatory and antibacterial effect...

    Authors: Yang Zhao, Chun-Pin Kao, Yuan-Shiun Chang and Yu-Ling Ho

    Citation: Chemistry Central Journal 2013 7:106

    Content type: Research article

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  30. The widespread utilization of organic compounds in modern society and their dispersion through wastewater have resulted in extensive contamination of source and drinking waters. The vast majority of these comp...

    Authors: Tarun Anumol, Sylvain Merel, Bradley O Clarke and Shane A Snyder

    Citation: Chemistry Central Journal 2013 7:104

    Content type: Research article

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  31. B-Lactam antibiotics are still the most common group of chemotherapeutic drugs that are used in the treatment of bacterial infections. However, due to their chemical instability the potential to apply them as ...

    Authors: Judyta Cielecka-Piontek, Magdalena Paczkowska, Kornelia Lewandowska, Boleslaw Barszcz, Przemyslaw Zalewski and Piotr Garbacki

    Citation: Chemistry Central Journal 2013 7:98

    Content type: Research article

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  32. In the study of biomolecular structures and interactions the polar hydrogen-π bonds (Hp-π) are an extensive molecular interaction type. In proteins 11 of 20 natural amino acids and in DNA (or RNA) all four nuc...

    Authors: Qi-Shi Du, Qing-Yan Wang, Li-Qin Du, Dong Chen and Ri-Bo Huang

    Citation: Chemistry Central Journal 2013 7:92

    Content type: Research article

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  33. Nifuroxazide (NF) is an oral nitrofuran antibiotic, having a wide range of bactericidal activity against gram positive and gram negative enteropathogenic organisms. It is formulated either in single form, as inte...

    Authors: Asmaa Ahmed El-Zaher and Marianne Alphonse Mahrouse

    Citation: Chemistry Central Journal 2013 7:90

    Content type: Research article

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  34. Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization mass spectrometric technique, allowing the analysis of bio-molecules and other macromolecules. The matrix molecules require certain char...

    Authors: Syed Ghulam Musharraf, Aisha Bibi, Najia Shahid, Muhammad Najam-ul-Haq, Nida Ambreen, Momin Khan, Khalid Mohammed Khan, M Iqbal Choudhary and Atta ur Rahman

    Citation: Chemistry Central Journal 2013 7:77

    Content type: Research article

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  35. The thermal decomposition of cephalexine, cefadroxil and cefoperazone under non-isothermal conditions using the TG, respectively DSC methods, was studied. In case of TG, a hyphenated technique, including EGA, ...

    Authors: Adriana Fuliaş, Gabriela Vlase, Titus Vlase, Codruţa Soica, Alina Heghes, Marius Craina and Ionuţ Ledeti

    Citation: Chemistry Central Journal 2013 7:70

    Content type: Research article

    Published on:

  36. Reliable values for method validity of organochlorine pesticides determination were investigated, in water by solid phase extraction and in sediment by Soxhlet extraction, followed by gas chromatography equipp...

    Authors: Naghmeh Saadati, Md Pauzi Abdullah, Zuriati Zakaria, Seyedeh Belin Tavakoli Sany, Majid Rezayi and Houshang Hassonizadeh

    Citation: Chemistry Central Journal 2013 7:63

    Content type: Research article

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  37. Snus is a smokeless oral tobacco product with a significant history of use in Sweden, where it is regulated under food legislation. Users place a small porous sachet or a pinch of loose snus between the upper ...

    Authors: Helena Digard, Nathan Gale, Graham Errington, Nicola Peters and Kevin McAdam

    Citation: Chemistry Central Journal 2013 7:55

    Content type: Research article

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  38. Perilla frutescens (L.) Britt. is not only an edible plant but also a traditional medicinal plant commonly used for treating common cold. It is widely cultivated in southern China. The anatomical parts of P. frut...

    Authors: Jing Liu, Yuklam Wan, Zhongzhen Zhao and Hubiao Chen

    Citation: Chemistry Central Journal 2013 7:61

    Content type: Research article

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  39. Lenalidomide (LND) is a new potent drug used for treatment of multiple myeloma. For its pharmacokinetic studies and therapeutic monitoring, a proper analytical method was required.

    Authors: Nasr Y Khalil, Ibrahim A Darwish, Tanveer A Wani and Abdel-Rahman A Al-Majed

    Citation: Chemistry Central Journal 2013 7:52

    Content type: Research article

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  40. Polygoni Multiflori Radix, He-Shou-Wu in Chinese, is a widely used traditional Chinese medicine. Clinically, water decoction is the major application form of He-Shou-Wu. Therefore, simultaneous determination of b...

    Authors: Ka-meng Lao, Dong-qi Han, Xiao-jia Chen, Jing Zhao, Tie-jie Wang and Shao-ping Li

    Citation: Chemistry Central Journal 2013 7:45

    Content type: Research article

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  41. The aim of this paper was the validation of a new analytical method based on the high-resolution continuum source flame atomic absorption spectrometry for the fast-sequential determination of several hazardous...

    Authors: Tiberiu Frentiu, Michaela Ponta and Raluca Hategan

    Citation: Chemistry Central Journal 2013 7:43

    Content type: Research article

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  42. Pao zhi is a common traditional approach that usually occurs before most herbs are prescribed whereby during processing, secondary plant metabolites are transformed, thus helping to increase potency, reduce to...

    Authors: Yubo Li, Yuming Wang, Lina Su, Lixin Li and Yanjun Zhang

    Citation: Chemistry Central Journal 2013 7:36

    Content type: Research article

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  43. The reaction of pharmacological active protic ionic liquid tris-(2-hydroxyethyl)ammonium 4-chlorophenylsulfanylacetate H+N(CH2CH2OH)3 ∙ (-OOCCH2SC6H4Cl-4) (1) with zinc or nickel chloride in a ratio of 2:1 afford...

    Authors: Anna N Mirskova, Sergey N Adamovich, Rudolf G Mirskov and Uwe Schilde

    Citation: Chemistry Central Journal 2013 7:34

    Content type: Preliminary communication

    Published on:

  44. Heterogeneous β-Alkyl (C12H25/C18H37) polyethyleneoxy (n = 0-20) propionamides [R(EO)nPD] represent new “hybrid” nonionic-ionic colloidal structures in the field of surface-active products (technical products). T...

    Authors: Adrian Riviş, Gabriel Bujanca and Teodor Traşcă

    Citation: Chemistry Central Journal 2013 7:31

    Content type: Research article

    Published on:

  45. New, simple and specific spectrophotometric methods and artificial neural network (ANN) were developed and validated in accordance with ICH guidelines for the simultaneous estimation of Olmesartan (OLM), Amlod...

    Authors: Hany W Darwish

    Citation: Chemistry Central Journal 2013 7:22

    Content type: Research article

    Published on:

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