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Analytical Chemistry

This section publishes articles in all areas of analytical chemistry including spectroscopy, crystallography, chromatography, imaging, chemometrics, data processing, and electrochemistry.

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  1. The present study aims to determine the carcinogenic and neurotoxic risks associated with acrylamide intake from cereal products. Analysis on a UPLC–MS/MS spectrometer revealed that oat-based and mixed cereals...

    Authors: Areej Merhi, Ghada El-Zakhem Naous, Ralph Daher, Martine Abboud, Mohamad Mroueh and Robin I. Taleb

    Citation: BMC Chemistry 2020 14:53

    Content type: Research article

    Published on:

  2. The study carried out a primary validation of Charm II tests for the detection of antimicrobial residues in aquaculture fish. The validation was performed according to European Commission Decision 2002/657/EC and...

    Authors: Aziz Kimera Mukota, Melanie Flore Kamini Gondam, Julie Judith Takadong Tsafack, James Sasanya, Wim Reybroeck, Muhammad Ntale, Steven Allan Nyanzi and Emmanuel Tebandeke

    Citation: BMC Chemistry 2020 14:32

    Content type: Research article

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  3. In this paper, a novel mercury-free electrochemical probe was constructed for the trace determination of octamethylcyclotetrasiloxane (D4) in some biological fluids by adsorptive stripping voltammetry. The platfo...

    Authors: Rashid Heidarimoghadam and Abbas Farmany

    Citation: BMC Chemistry 2020 14:29

    Content type: Research article

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  4. Congo red (CR) is an anionic azo dye widely used in many industries including pharmaceutical, textile, food and paint industries. The disposal of huge amount of CR into the various streams of water has posed a...

    Authors: Syed Rizwan Shafqat, Showkat Ahmad Bhawani, Salma Bakhtiar and Mohamad Nasir Mohamad Ibrahim

    Citation: BMC Chemistry 2020 14:27

    Content type: Research article

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  5. In this paper, we describe synthesis and application of an iron porphyrinc metal–organic framework PCN-222(Fe) for solid phase extraction of aspartame, an artificial non-saccharine sweetener, from gum, juice a...

    Authors: Zahra Safaei Moghaddam, Massoud Kaykhaii, Mostafa Khajeh and Ali Reza Oveisi

    Citation: BMC Chemistry 2020 14:19

    Content type: Research article

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  6. In this study, a functionalized multiwalled carbon nanotube (MWCNT)-coated solid-phase microextraction (SPME) fiber was developed for concentrating analytes in aqueous samples. Sodium deoxycholate (NaDC) was u...

    Authors: Xueqing Zhou, Yanli Xie, Zhendong Zhao and Wenyan Fu

    Citation: BMC Chemistry 2020 14:15

    Content type: Research article

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  7. To formulate a nanoformulation (PLGA-NPs) and to improve brain bioavailability for thymoquinone (THQ) through intranasal (i.n.) drug delivery, using a newly UHPLC-PDA developed the method and validated. Five d...

    Authors: Niyaz Ahmad, Rizwan Ahmad, Sadiq Al Qatifi, Mahdi Alessa, Hassan Al Hajji and Md Sarafroz

    Citation: BMC Chemistry 2020 14:10

    Content type: Research article

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  8. Corydalis yanhusuo W.T. Wang alkaloids are mainly divided into three categories: protoberberine, prototropine and aporphine alkaloids. Therefore, we have taken into account these three alkaloid contents when extr...

    Authors: Yongping Zhang, Zuhua Wang, Jian Xu, Fangfang Yang, Chuanyang Dai, Weijie Xie, Zhu Liang and Songbo Su

    Citation: BMC Chemistry 2020 14:9

    Content type: Research article

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  9. Extensive bioactivities of alkaloids from the genus Macleaya (Macleaya cordata (Willd.) R. Br. and Macleaya microcarpa (Maxim.) Fedde) have been widely reported, as well as more and more concerned from the scient...

    Authors: Chunmei Sai, Jian’an Wang, Binjie Li, Lin Ding, Huiyun Wang, Qibao Wang, Huiming Hua, Fangpeng Zhang and Qiang Ren

    Citation: BMC Chemistry 2020 14:5

    Content type: Research article

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  10. A novel polystyrene sulfonate sodium (PSS) magnetic material was prepared by surface-initiated atom transfer radical polymerization (SI-ATRP). The starting materials were brominated magnetic material as the ca...

    Authors: Huachun Liu, Bolin Gong, Yanqiang Zhou, Zhian Sun, Xiaoxiao Wang and Shanwen Zhao

    Citation: BMC Chemistry 2020 14:3

    Content type: Research article

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  11. Mainstream tobacco smoke is a complex and dynamic aerosol, consisting of particulate and vapour phases. Most approaches to determine mainstream smoke toxicant yields are based on offline techniques that limit ...

    Authors: Jenni Hawke, Graham Errington and Matthias Bente von Frowein

    Citation: BMC Chemistry 2019 13:135

    Content type: Research article

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  12. Safety, environmental and economic setbacks are driving industries to find greener approaches to extract bioactive compounds from natural resources. Pressurized hot water extraction (PHWE) is among the solvent...

    Authors: Noor Hidayah Mohd Jusoh, Atiqah Subki, Swee Keong Yeap, Ken Choy Yap and Indu Bala Jaganath

    Citation: BMC Chemistry 2019 13:134

    Content type: Research article

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  13. The current work deals with fabrication and validation of a new highly Fe3+ selective sensor based on benzo-18-crown-6 (b-18C6) using the potentiometric method. The proposed sensor revealed satisfactory performan...

    Authors: Somayeh Badakhshan, Saeid Ahmadzadeh, Anoushiravan Mohseni-Bandpei, Majid Aghasi and Amir Basiri

    Citation: BMC Chemistry 2019 13:131

    Content type: Research article

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  14. In this work, using DNA and exonuclease-I (Exo-I) as signal amplification strategy, a novel and facile electrochemical aptasensor was constructed for fumonisin B1 (FB1) detection. The G-rich complementary DNA (cD...

    Authors: Min Wei, Fei Zhao, Shuo Feng and Huali Jin

    Citation: BMC Chemistry 2019 13:129

    Content type: Research article

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  15. In situ analysis of odor is an important approach to connect odor with chemical composition. However, it is difficult to conduct a rapid direct analysis of the odor sample because of low analyte concentration ...

    Authors: Shihao Sun, Yihan Zhang, Peng Li, Hui Xi, Lei Wu, Jianxun Zhang, Guixin Peng and Yue Su

    Citation: BMC Chemistry 2019 13:125

    Content type: Research article

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  16. The study aims to develop simple, sensitive, and selective methods for detecting methylphenidate in its bulk, dosage form and human urine. Sensing materials include β-cyclodextrin (β-CD), γ-cyclodextrin (γ-CD)...

    Authors: Haitham AlRabiah, Mohammed Abounassif, Haya I. Aljohar and Gamal Abdel-Hafiz Mostafa

    Citation: BMC Chemistry 2019 13:121

    Content type: Research article

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  17. In the present study two different RSLC columns, Acclaim RSLC 120 C18, 5.0 µm, 4.6 × 150 mm (column A) and Acclaim RSLC 120 C18, 2.2 µm, 2.1 × 100 mm (Column B) were utilized for the analysis of velpatasvir (V...

    Authors: Moustapha Eid Moustapha, Rania Mohamed El-Gamal and Fathalla Fathalla Belal

    Citation: BMC Chemistry 2019 13:118

    Content type: Research article

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  18. Prostate cancer (PC) is the sixth most common cancer type in the world, which causes approximately 10% of total cancer fatalities. The detection of protein biomarkers in body fluids is the key topic for the di...

    Authors: Li Xu, Yanli Wen, Santosh Pandit, Venkata R. S. S. Mokkapati, Ivan Mijakovic, Yan Li, Min Ding, Shuzhen Ren, Wen Li and Gang Liu

    Citation: BMC Chemistry 2019 13:112

    Content type: Mini review

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  19. Paracetamol is an analgesic-antipyretic drug and Ibuprofen is a non-steroidal anti-inflammatory drug. They are co-formulated as tablets to improve analgesia, to simplify prescribing and to improve patient comp...

    Authors: Christine M. El-Maraghy and Nesrine T. Lamie

    Citation: BMC Chemistry 2019 13:99

    Content type: Research article

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  20. Sodium benzoate (SB) is widely used as a preservative in food industry, and bovine serum albumin (BSA) is a major carrier protein similar to human serum albumin (HSA), the study of the binding between the two ...

    Authors: Jing Yu, Jian-Yi Liu, Wei-Ming Xiong, Xiao-Yue Zhang and Yue Zheng

    Citation: BMC Chemistry 2019 13:95

    Content type: Research article

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  21. Flickingeria fimbriata is commonly applied in China as a traditional Chinese medicine (TCM), however the quality control of it is incomplete. In this work, we aim to identify and quantify the structures of C-glyc...

    Authors: Yawen Wang, Zhiyun Liang, Xian Liao, Chujuan Zhou, Zhenshan Xie, Sha Zhu, Gang Wei and Yuechun Huang

    Citation: BMC Chemistry 2019 13:94

    Content type: Research article

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  22. Bidi, an indigenous form of cigarette in South Asian countries, is popular because of its low cost and multi-flavored variants. Although recent studies have shown that bidi smokers suffer from various adverse ...

    Authors: Omobola Ajoke Oladipupo, Dibyendu Dutta and Ngee Sing Chong

    Citation: BMC Chemistry 2019 13:93

    Content type: Research article

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  23. Atractylodis rhizoma, is the dried rhizomes of Atractylodes lancea (Thunb.) DC. or A. chinensis (DC.) Koidz. Both of two are pharmacologically and economically important, while with differences in efficacy. There...

    Authors: Dan Zhuang, Jing Qin, Hui-yang Wang, Yi Zhang, Chun-yao Liu, Qing-qing Ding and Guang-ping Lv

    Citation: BMC Chemistry 2019 13:92

    Content type: Research article

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  24. Lipophilicity is a physicochemical property of an essential importance in medicinal chemistry; therefore, fast and reliable measurement of lipophilicity will affect greatly the drug discovery process.

    Authors: Heba Elmansi, Jenny Jeehan Nasr, Azza H. Rageh, Mohamed I. El-Awady, Ghada S. Hassan, Hatem A. Abdel-Aziz and Fathalla Belal

    Citation: BMC Chemistry 2019 13:84

    Content type: Research article

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  25. A simple, rapid and sensitive ultrahigh performance liquid chromatographic method was developed for the determination of the anti-diabetic drug: empagliflozin (EMPA) and three related substances in spiked huma...

    Authors: Mokhtar M. Mabrouk, Suzan M. Soliman, Heba M. El-Agizy and Fotouh R. Mansour

    Citation: BMC Chemistry 2019 13:83

    Content type: Research article

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  26. Highly sensitive and selective liquid chromatography/tandem mass spectrometry (LC–MS/MS) method was developed and validated for the simultaneous estimation of the recently approved oral hypoglycemic mixture; m...

    Authors: Dalia Mohamed, Mona S. Elshahed, Tamer Nasr, Nageh Aboutaleb and Ola Zakaria

    Citation: BMC Chemistry 2019 13:82

    Content type: Research article

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  27. The dynamic changes of secondary metabolites and tyrosinase activity of Malus pumila flowers were investigated during blooming for full use of M. pumila flowers. Phlorizin, astragalin and afzelin were selected as...

    Authors: Lili Cui, Xingzi Hou, Wenjing Li, Yuchun Leng, Yang Zhang, Xinjuan Li, Yangyang Hou, Zhenhua Liu and Wenyi Kang

    Citation: BMC Chemistry 2019 13:81

    Content type: Research article

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  28. Comtrex® tablets composed of paracetamol, pseudoephedrine and brompheniramine are widely used for relieving symptoms related to common cold. This study has overcome the challenging dosage form ratio (250:15:1) an...

    Authors: Souha Hosam Youssef, Dalia Mohamed, Maha Abdel Monem Hegazy and Amr Badawey

    Citation: BMC Chemistry 2019 13:78

    Content type: Research article

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  29. 5-Hydroxytryptamine (also known as 5-HT, serotonin) is one of the monoamine neurotransmitters which is distributed widely in plasma and brain of mammals and plays important roles in physiological manipulations...

    Authors: Qiangqiang He, Maoru Li, Xuechun Wang, Zhenjiang Xia, Yuzhi Du, Yan Li, Lixin Wei and Jing Shang

    Citation: BMC Chemistry 2019 13:76

    Content type: Methodology article

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  30. One of the major causes of mortality all over the world is chronic obstructive pulmonary disease (COPD). Recently approved combined inhaler of formoterol fumarate (FF) and glycopyrronium bromide (GLY) has been...

    Authors: Yomna A. Salem, Mohammed E. A. Hammouda, Mohamed A. Abu El-Enin and Saadia M. El-Ashry

    Citation: BMC Chemistry 2019 13:75

    Content type: Research article

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  31. Parabens and sorbic acid are commonly used as food preservatives due to their antimicrobial effect. However, their use in foods for infants and young children is not permitted in the European Union. Previous s...

    Authors: Theodoros Potouridis, Alena Knauz, Elisabeth Berger and Wilhelm Püttmann

    Citation: BMC Chemistry 2019 13:70

    Content type: Research article

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  32. Nowadays, there is a growing interest in innovative and more efficient therapeutics—biopharmaceuticals, based on peptides or proteins. There are increased demands on quality control of such therapeutics. One o...

    Authors: Juraj Piestansky, Jaroslav Galba, Dominika Olesova, Branislav Kovacech and Andrej Kovac

    Citation: BMC Chemistry 2019 13:64

    Content type: Research article

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  33. In this study, a simple one-step ionic liquid-based ultrasound-assisted dispersive liquid–liquid microextraction technique was coupled with high-performance liquid chromatography for the analysis of four pyret...

    Authors: Yiyi Liao, Yuge Hou, Yan Zhong, Hong Chen, Chang Xu, Makoto Tsunoda, Yingxia Zhang, Shiming Deng and Yanting Song

    Citation: BMC Chemistry 2019 13:61

    Content type: Research article

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  34. This paper describes the application of response surface methodology (RSM) to develop a miniaturized metal organic framework based pipette-tip solid phase extraction for the extraction of malachite green (MG),...

    Authors: Sayyed Hossein Hashemi, Massoud Kaykhaii, Ahmad Jamali Keikha, Elahe Mirmoradzehi and Ghasem Sargazi

    Citation: BMC Chemistry 2019 13:59

    Content type: Research article

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  35. The occurrence of emerging pollutants like pharmaceuticals and related compounds in the aquatic and terrestrial environments is of increasing concern. Ciprofloxacin is one of the pharmaceuticals which is activ...

    Authors: Teshome Gezahegn, Bisratewongel Tegegne, Feleke Zewge and Bhagwan Singh Chandravanshi

    Citation: BMC Chemistry 2019 13:28

    Content type: Research article

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  36. Measuring concentrations of metabolites of estradiol and progesterone in urine, instead of measuring serum concentrations, is common in research and also is used in patient care. The primary aim of this study ...

    Authors: Mark Newman, Suzanne M. Pratt, Desmond A. Curran and Frank Z. Stanczyk

    Citation: BMC Chemistry 2019 13:20

    Content type: Methodology article

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  37. Chaenomelis Fructus is a type of traditional medicine used in China. At present, the quality standard of Chaenomelis Fructus is mainly based on the content of each component as a control index, lacking overall...

    Authors: Lili Zhu, Lexia Fang, Zongjin Li, Xiaomei Xie and Ling Zhang

    Citation: BMC Chemistry 2019 13:7

    Content type: Research article

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  38. Ligand exchange method is introduced as an alternative to Job’s and mole ratio methods for studying the stoichiometry of relatively weak metal complexes in solutions. The method involves adding varying amounts...

    Authors: Mokhtar Mabrouk, Sherin F. Hammad, Mohamed A. Abdelaziz and Fotouh R. Mansour

    Citation: Chemistry Central Journal 2018 12:143

    Content type: Research Article

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  39. Differences in health risks between different styles of smokeless tobacco products (STPs) have prompted interest in their relative levels of toxic chemicals. We report here the development of methods for the a...

    Authors: Kevin McAdam, Trevor Enos, Carol Goss, Harriet Kimpton, Arif Faizi, Steve Edwards, Christopher Wright, Andrew Porter and Brad Rodu

    Citation: Chemistry Central Journal 2018 12:142

    Content type: Research Article

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  40. There is considerable interest in the chemical composition of smokeless tobacco products (STPs), owing to health concerns associated with their use. Previous studies have documented levels of 210Po, 210Pb and ura...

    Authors: K. McAdam, H. Kimpton, A. Porter, C. Liu, A. Faizi, M. Mola, J. McAughey and B. Rodu

    Citation: Chemistry Central Journal 2017 11:131

    Content type: Research Article

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  41. Protein–protein interactions are responsible for many biological processes, and the study of how proteins undergo a conformational change induced by other proteins in the immobilized state can help us to under...

    Authors: Xiaoning Zhang and Hongmei Hu

    Citation: Chemistry Central Journal 2017 11:128

    Content type: Research article

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  42. This study was conducted to develop fast and cost effective methods for the determination of caffeine in green coffee beans. In the present work direct determination of caffeine in aqueous solution of green co...

    Authors: Blen Weldegebreal, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Citation: Chemistry Central Journal 2017 11:126

    Content type: Research Article

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  43. The conditions of heating, ionic liquid-based ultrasonic-assisted extraction combined with reverse-phase high performance liquid chromatography were optimized to simultaneously isolate and determinate brazilin...

    Authors: Zhaoyang Xia, Dongdong Li, Qing Li, Yan Zhang and Wenyi Kang

    Citation: Chemistry Central Journal 2017 11:114

    Content type: Research article

    Published on: