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Analytical Chemistry

Edited by Yi-Lun Ying
Scope: This section publishes articles in all areas of analytical chemistry including spectroscopy, crystallography, chromatography, imaging, chemometrics, data processing, and electrochemistry.

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  1. Content type: Mini review

    Prostate cancer (PC) is the sixth most common cancer type in the world, which causes approximately 10% of total cancer fatalities. The detection of protein biomarkers in body fluids is the key topic for the di...

    Authors: Li Xu, Yanli Wen, Santosh Pandit, Venkata R. S. S. Mokkapati, Ivan Mijakovic, Yan Li, Min Ding, Shuzhen Ren, Wen Li and Gang Liu

    Citation: BMC Chemistry 2019 13:112

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  2. Content type: Research article

    Paracetamol is an analgesic-antipyretic drug and Ibuprofen is a non-steroidal anti-inflammatory drug. They are co-formulated as tablets to improve analgesia, to simplify prescribing and to improve patient comp...

    Authors: Christine M. El-Maraghy and Nesrine T. Lamie

    Citation: BMC Chemistry 2019 13:99

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  3. Content type: Research article

    Sodium benzoate (SB) is widely used as a preservative in food industry, and bovine serum albumin (BSA) is a major carrier protein similar to human serum albumin (HSA), the study of the binding between the two ...

    Authors: Jing Yu, Jian-Yi Liu, Wei-Ming Xiong, Xiao-Yue Zhang and Yue Zheng

    Citation: BMC Chemistry 2019 13:95

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  4. Content type: Research article

    Flickingeria fimbriata is commonly applied in China as a traditional Chinese medicine (TCM), however the quality control of it is incomplete. In this work, we aim to identify and quantify the structures of C-glyc...

    Authors: Yawen Wang, Zhiyun Liang, Xian Liao, Chujuan Zhou, Zhenshan Xie, Sha Zhu, Gang Wei and Yuechun Huang

    Citation: BMC Chemistry 2019 13:94

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  5. Content type: Research article

    Bidi, an indigenous form of cigarette in South Asian countries, is popular because of its low cost and multi-flavored variants. Although recent studies have shown that bidi smokers suffer from various adverse ...

    Authors: Omobola Ajoke Oladipupo, Dibyendu Dutta and Ngee Sing Chong

    Citation: BMC Chemistry 2019 13:93

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  6. Content type: Research article

    Atractylodis rhizoma, is the dried rhizomes of Atractylodes lancea (Thunb.) DC. or A. chinensis (DC.) Koidz. Both of two are pharmacologically and economically important, while with differences in efficacy. There...

    Authors: Dan Zhuang, Jing Qin, Hui-yang Wang, Yi Zhang, Chun-yao Liu, Qing-qing Ding and Guang-ping Lv

    Citation: BMC Chemistry 2019 13:92

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  7. Content type: Research article

    Lipophilicity is a physicochemical property of an essential importance in medicinal chemistry; therefore, fast and reliable measurement of lipophilicity will affect greatly the drug discovery process.

    Authors: Heba Elmansi, Jenny Jeehan Nasr, Azza H. Rageh, Mohamed I. El-Awady, Ghada S. Hassan, Hatem A. Abdel-Aziz and Fathalla Belal

    Citation: BMC Chemistry 2019 13:84

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  8. Content type: Research article

    A simple, rapid and sensitive ultrahigh performance liquid chromatographic method was developed for the determination of the anti-diabetic drug: empagliflozin (EMPA) and three related substances in spiked huma...

    Authors: Mokhtar M. Mabrouk, Suzan M. Soliman, Heba M. El-Agizy and Fotouh R. Mansour

    Citation: BMC Chemistry 2019 13:83

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  9. Content type: Research article

    Highly sensitive and selective liquid chromatography/tandem mass spectrometry (LC–MS/MS) method was developed and validated for the simultaneous estimation of the recently approved oral hypoglycemic mixture; m...

    Authors: Dalia Mohamed, Mona S. Elshahed, Tamer Nasr, Nageh Aboutaleb and Ola Zakaria

    Citation: BMC Chemistry 2019 13:82

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  10. Content type: Research article

    The dynamic changes of secondary metabolites and tyrosinase activity of Malus pumila flowers were investigated during blooming for full use of M. pumila flowers. Phlorizin, astragalin and afzelin were selected as...

    Authors: Lili Cui, Xingzi Hou, Wenjing Li, Yuchun Leng, Yang Zhang, Xinjuan Li, Yangyang Hou, Zhenhua Liu and Wenyi Kang

    Citation: BMC Chemistry 2019 13:81

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  11. Content type: Research article

    Comtrex® tablets composed of paracetamol, pseudoephedrine and brompheniramine are widely used for relieving symptoms related to common cold. This study has overcome the challenging dosage form ratio (250:15:1) an...

    Authors: Souha Hosam Youssef, Dalia Mohamed, Maha Abdel Monem Hegazy and Amr Badawey

    Citation: BMC Chemistry 2019 13:78

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  12. Content type: Methodology article

    5-Hydroxytryptamine (also known as 5-HT, serotonin) is one of the monoamine neurotransmitters which is distributed widely in plasma and brain of mammals and plays important roles in physiological manipulations...

    Authors: Qiangqiang He, Maoru Li, Xuechun Wang, Zhenjiang Xia, Yuzhi Du, Yan Li, Lixin Wei and Jing Shang

    Citation: BMC Chemistry 2019 13:76

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  13. Content type: Research article

    One of the major causes of mortality all over the world is chronic obstructive pulmonary disease (COPD). Recently approved combined inhaler of formoterol fumarate (FF) and glycopyrronium bromide (GLY) has been...

    Authors: Yomna A. Salem, Mohammed E. A. Hammouda, Mohamed A. Abu El-Enin and Saadia M. El-Ashry

    Citation: BMC Chemistry 2019 13:75

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  14. Content type: Research article

    Parabens and sorbic acid are commonly used as food preservatives due to their antimicrobial effect. However, their use in foods for infants and young children is not permitted in the European Union. Previous s...

    Authors: Theodoros Potouridis, Alena Knauz, Elisabeth Berger and Wilhelm Püttmann

    Citation: BMC Chemistry 2019 13:70

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  15. Content type: Research article

    Nowadays, there is a growing interest in innovative and more efficient therapeutics—biopharmaceuticals, based on peptides or proteins. There are increased demands on quality control of such therapeutics. One o...

    Authors: Juraj Piestansky, Jaroslav Galba, Dominika Olesova, Branislav Kovacech and Andrej Kovac

    Citation: BMC Chemistry 2019 13:64

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  16. Content type: Research article

    In this study, a simple one-step ionic liquid-based ultrasound-assisted dispersive liquid–liquid microextraction technique was coupled with high-performance liquid chromatography for the analysis of four pyret...

    Authors: Yiyi Liao, Yuge Hou, Yan Zhong, Hong Chen, Chang Xu, Makoto Tsunoda, Yingxia Zhang, Shiming Deng and Yanting Song

    Citation: BMC Chemistry 2019 13:61

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  17. Content type: Research article

    This paper describes the application of response surface methodology (RSM) to develop a miniaturized metal organic framework based pipette-tip solid phase extraction for the extraction of malachite green (MG),...

    Authors: Sayyed Hossein Hashemi, Massoud Kaykhaii, Ahmad Jamali Keikha, Elahe Mirmoradzehi and Ghasem Sargazi

    Citation: BMC Chemistry 2019 13:59

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  18. Content type: Research article

    The occurrence of emerging pollutants like pharmaceuticals and related compounds in the aquatic and terrestrial environments is of increasing concern. Ciprofloxacin is one of the pharmaceuticals which is activ...

    Authors: Teshome Gezahegn, Bisratewongel Tegegne, Feleke Zewge and Bhagwan Singh Chandravanshi

    Citation: BMC Chemistry 2019 13:28

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  19. Content type: Methodology article

    Measuring concentrations of metabolites of estradiol and progesterone in urine, instead of measuring serum concentrations, is common in research and also is used in patient care. The primary aim of this study ...

    Authors: Mark Newman, Suzanne M. Pratt, Desmond A. Curran and Frank Z. Stanczyk

    Citation: BMC Chemistry 2019 13:20

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  20. Content type: Research article

    Chaenomelis Fructus is a type of traditional medicine used in China. At present, the quality standard of Chaenomelis Fructus is mainly based on the content of each component as a control index, lacking overall...

    Authors: Lili Zhu, Lexia Fang, Zongjin Li, Xiaomei Xie and Ling Zhang

    Citation: BMC Chemistry 2019 13:7

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  21. Content type: Research Article

    Ligand exchange method is introduced as an alternative to Job’s and mole ratio methods for studying the stoichiometry of relatively weak metal complexes in solutions. The method involves adding varying amounts...

    Authors: Mokhtar Mabrouk, Sherin F. Hammad, Mohamed A. Abdelaziz and Fotouh R. Mansour

    Citation: Chemistry Central Journal 2018 12:143

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  22. Content type: Research Article

    Differences in health risks between different styles of smokeless tobacco products (STPs) have prompted interest in their relative levels of toxic chemicals. We report here the development of methods for the a...

    Authors: Kevin McAdam, Trevor Enos, Carol Goss, Harriet Kimpton, Arif Faizi, Steve Edwards, Christopher Wright, Andrew Porter and Brad Rodu

    Citation: Chemistry Central Journal 2018 12:142

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  23. Content type: Research Article

    There is considerable interest in the chemical composition of smokeless tobacco products (STPs), owing to health concerns associated with their use. Previous studies have documented levels of 210Po, 210Pb and ura...

    Authors: K. McAdam, H. Kimpton, A. Porter, C. Liu, A. Faizi, M. Mola, J. McAughey and B. Rodu

    Citation: Chemistry Central Journal 2017 11:131

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  24. Content type: Research article

    Protein–protein interactions are responsible for many biological processes, and the study of how proteins undergo a conformational change induced by other proteins in the immobilized state can help us to under...

    Authors: Xiaoning Zhang and Hongmei Hu

    Citation: Chemistry Central Journal 2017 11:128

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  25. Content type: Research Article

    This study was conducted to develop fast and cost effective methods for the determination of caffeine in green coffee beans. In the present work direct determination of caffeine in aqueous solution of green co...

    Authors: Blen Weldegebreal, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Citation: Chemistry Central Journal 2017 11:126

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  26. Content type: Research article

    The conditions of heating, ionic liquid-based ultrasonic-assisted extraction combined with reverse-phase high performance liquid chromatography were optimized to simultaneously isolate and determinate brazilin...

    Authors: Zhaoyang Xia, Dongdong Li, Qing Li, Yan Zhang and Wenyi Kang

    Citation: Chemistry Central Journal 2017 11:114

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  27. Content type: Research article

    Khat (Catha edulis Forsk) is an evergreen shrub of the Celastraceae family. It is widely cultivated in Yemen and East Africa, where its fresh leaves are habitually chewed for their momentary pleasures and stimula...

    Authors: Minaleshewa Atlabachew, Bhagwan Singh Chandravanshi and Mesfin Redi-Abshiro

    Citation: Chemistry Central Journal 2017 11:107

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  28. Content type: Research article

    Jujube extract is commonly used as a food additive and flavoring. The unique jujube aroma and the mild sweet aroma of the extract are critical factors that determine product quality and affect consumer accepta...

    Authors: Shi-Hao Sun, Guo-Bi Chai, Peng Li, Jian-Ping Xie and Yue Su

    Citation: Chemistry Central Journal 2017 11:101

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  29. Content type: Research article

    The combination between cetirizine (CET), phenylpropanolamine (PPA) and nimesulide (NMS) under trade name Nemeriv Cp tablet is prescribed for nasal congestion, cold, sneezing, and allergy. Among all published ...

    Authors: Fatma Ahmed Aly, Nahed EL-Enany, Heba Elmansi and Amany Nabil

    Citation: Chemistry Central Journal 2017 11:99

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  30. Content type: Research article

    Chamomile, a well-known medicinal plant, is a rich source of bioactive compounds, among which two coumarin derivatives, umbelliferone and herniarin, are often found in its extracts. Chamomile extracts have fou...

    Authors: Maja Molnar, Nikolina Mendešević, Drago Šubarić, Ines Banjari and Stela Jokić

    Citation: Chemistry Central Journal 2017 11:78

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  31. Content type: Research article

    This study has demonstrated the use of crystallography, topology and graph set analysis in the description and classification of the complex hydrogen bonded network of triamterene. The aim is to give a brief o...

    Authors: David S. Hughes, Amit Delori, Abida Rehman and William Jones

    Citation: Chemistry Central Journal 2017 11:63

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  32. Content type: Research article

    A simple, rapid and accurate stability-indicating reverse phase high performance liquid chromatography (RP-HPLC) was developed and validated for the determination of brimonidine tartrate in brimonidine tartrat...

    Authors: Jianguo Sun, Xiuwen Zhang and Taomin Huang

    Citation: Chemistry Central Journal 2017 11:62

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  33. Content type: Review

    In these recent years, magnetite (Fe3O4) has witnessed a growing interest in the scientific community as a potential material in various fields of application namely in catalysis, biosensing, hyperthermia treatme...

    Authors: Essy Kouadio Fodjo, Koffi Mouroufié Gabriel, Brou Yapi Serge, Dan Li, Cong Kong and Albert Trokourey

    Citation: Chemistry Central Journal 2017 11:58

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  34. Content type: Research article

    Clinacanthus nutans Lindau is a well-known plant, native to tropical Asian countries. Reports on this plant that is rich in phenolic compounds have focused on its therapeutic anti-infl...

    Authors: Intan Soraya Che Sulaiman, Mahiran Basri, Hamid Reza Fard Masoumi, Wei Jian Chee, Siti Efliza Ashari and Maznah Ismail

    Citation: Chemistry Central Journal 2017 11:54

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  35. Content type: Research article

    Vandetanib (VNT) is a new oral tyrosine kinase inhibitor that acts mainly by inhibiting vascular endothelial growth factor receptor (VEGFR). Fast, specific, sensitive and validated LC–MS/MS was established for...

    Authors: Sawsan M. Amer, Adnan A. Kadi, Hany W. Darwish and Mohamed W. Attwa

    Citation: Chemistry Central Journal 2017 11:45

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  36. Content type: Research article

    Analysis of complex mixture containing three or more components represented a challenge for analysts. New smart spectrophotometric methods have been recently evolved with no limitation. A study of different no...

    Authors: Ekram H. Mohamed, Hayam M. Lotfy, Maha A. Hegazy and Shereen Mowaka

    Citation: Chemistry Central Journal 2017 11:43

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  37. Content type: Research article

    Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. A combination of indacaterol maleate with glycopyrronium bromide has recently been approved as a once-daily m...

    Authors: Sahar Zayed and Fathalla Belal

    Citation: Chemistry Central Journal 2017 11:36

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  38. Content type: Research article

    Natural based composites of hydroxyapatite/Gum Arabic designed for removal of toxic metal arsenic (III) from waste water were synthesized and evaluated. Several composites with various compositions were prepar...

    Authors: N. Akartasse, E. Mejdoubi, B. Razzouki, K. Azzaoui, S. Jodeh, O. Hamed, M. Ramdani, A. Lamhamdi, M. Berrabah, I. Lahmass, W. Jodeh and S. El Hajjaji

    Citation: Chemistry Central Journal 2017 11:33

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  39. Content type: Research article

    Traditional fermented alcoholic beverages are indigenous to a particular area and are prepared by the local people using an age-old techniques and locally available raw materials. The main objective of this wo...

    Authors: Ayalew Debebe, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Citation: Chemistry Central Journal 2017 11:27

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  40. Content type: Research article

    The extraction of bioactive compounds from herbal materials requires optimization in order to recover the highest active dose. Response surface methodology was used to optimize variables affecting the microwav...

    Authors: Ali Ghasemzadeh, Hawa Z. E. Jaafar, Asmah Rahmat and Mallappa Kumara Swamy

    Citation: Chemistry Central Journal 2017 11:5

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  41. Content type: Research article

    Ombitasvir/paritaprevir/ritonavir/dasabuvir (Viekira Pak®) are the newest medicines approved for use in the treatment of hepatitis C virus (HCV) and are available in tablet form as an oral combination. Specifical...

    Authors: Nourah Zoman Al-Zoman, Hadir Mohamed Maher and Amal Al-Subaie

    Citation: Chemistry Central Journal 2017 11:1

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  42. Content type: Research article

    The diluted aerosols from a cigarette (3R4F) and an e-cigarette (Vype ePen) were compared in two commercially available in vitro exposure systems: the Borgwaldt RM20S and Vitrocell VC10. Dosimetry was assessed...

    Authors: Jason Adamson, David Thorne, Benjamin Zainuddin, Andrew Baxter, John McAughey and Marianna Gaça

    Citation: Chemistry Central Journal 2016 10:74

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  43. Content type: Research Article

    Loratadine is a commonly used selective non-sedating antihistaminic drug. Desloratadine is the active metabolite of loratadine and, in addition, a potential impurity in loratadine bulk powder stated by the Uni...

    Authors: Fathalla Belal, Sawsan Abd El-Razeq, Mohamed El-Awady, Sahar Zayed and Sona Barghash

    Citation: Chemistry Central Journal 2016 10:79

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