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Table 1 Results of the antimicrobial screening of ligand 4 and its metal complexes 5, 6

From: A new antimicrobial PVC-based polymeric material incorporating bisacylthiourea complexes

Compound

Tested Microorganisms

(G ram negative Bacteria)

(Gram positive Bacteria)

(Fungi)

E.Coli

P.Aeruginosa

S. Pneumoniae

B. subtilis

C. albicans

A. fumigatus

 

Inhibition zone diameter (mm/mg sample)

Gentamicin(G-)

19.9 ± 0.3

17.3 ± 0.1

-------

-------

-------

-------

Ampicillin (G+)

-------

-------

23.8 ± 0.2

32.4 ± 0.3

-------

-------

Amphotericin B

-------

-------

-------

-------

25.4 ± 0.1

23.7 ± 0.1

Control: DMSO

NA

NA

NA

NA

NA

NA

4

15.1 ± 0.25

13.2 ± 0.58

18.1 ± 0.25

16.3 ± 0.58

16.2 ± 0.25

14.3 ± 0.58

5

16.2 ± 0.25

13.9 ± 0.58

17.2 ± 0.63

18.6 ± 0.63

17.1 ± 0.25

15.2 ± 0.58

6

19.2 ± 0.63

16.2 ± 0.58

18.3 ± 0.58

19.6 ± 0.44

21.3 ± 0.72

20.6 ± 1.2

  1. NA = absence of activity; the data are expressed in the form of mean ± standard deviation