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Table 9 Kinetic parameter for the Forced degradation of MNT under different stress conditions

From: Green quality by design HPLC approach for the simultaneous determination of Bilastine and Montelukast

Stress condition

Temperature, °C

Time, h

% Degradation

t1/2, h

Acidic (0.3 M HCl)

40

3

37.38

1.67

Basic (0.3 M NaOH)

40

3

31.7

1.8

Thermal

70

3

27.87

3.7

UV radiation (254 nm)

25

3

35.21

4.01

Oxidative (10% H2O2)

25

3

18.26

9.12