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Table 8 Assay results for the determination of the studied drugs in their prepared tablets by the proposed HPLC method

From: Green quality by design HPLC approach for the simultaneous determination of Bilastine and Montelukast

 

Proposed method

Comparison method

Amount taken (µg/mL)

Amount found (µg/mL)

% Found

% Found

BIL

MNT

BIL

MNT

BIL

MNT

BIL

MNT

 

10.0

5.0

10.15

4.95

101.53

99.07

100.79

100.85

20.0

10.0

19.77

10.07

98.85

100.70

98.95

98.87

40.0

20.0

40.07

19.98

100.19

99.88

100.39

100.42

Mean

 

100.19

99.88

100.04

100.05

 ± S.D

1.34

0.82

0.97

1.04

t-test

0.17

0.21

(2.45)*

F-test

1.91

1.61

(9.28)*

  1. Each result is the average of three separate determinations
  2. *The figures between parentheses are the tabulated t and F values at P = 0.05 [29]
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BMC Chemistry

ISSN: 2661-801X

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