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Table 3 Greenness study and comparison of the proposed method with the reported one

From: Exploiting the power of UPLC in separation and simultaneous determination of pholcodine, guaiacol along with three specified guaiacol impurities

Method

Elution time (min)

Application

Greenness assessment via AGREE

Reported method [22]

7

Simultaneous determination of PHL and GUA in presence of PHL oxidative degradation product

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Proposed method

3

Simultaneous determination of the PHL, GUA, and three specified GUA impurities in their quinary mixture

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