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Table 4 Assay results for determination of FRS in its dosage forms by the proposed method

From: Use of green fluorescent nano-sensors for the determination of furosemide in biological samples and pharmaceutical preparations

Preparation

Proposed method

Comparison methods [4]

Amount takena

(µg/mL)

Amount found

(µg/mL)

% Recovery

a-Lasix20 mg/2mLampoules

0.1

0.98

98.96

101.03

0.2

0.202

101.04

98.97

0.3

0.299

99.65

100.34

‾x

 

99.88

100.11

± SD

± 1.06

± 1.05

% RSD

1.06

 

% Error

0.61

t-test

0.27(2.77)b

F-test

1.02(19)b

b-Lasix® 40 mg

tablets

0.1

0.102

102.08

102.90

0.2

0.196

97.92

97.09

0.3

0.302

100.69

100.96

 

100.23

100.31

± SD

± 2.12

± 2.96

% RSD

2.11

 

% Error

1.22

t-test

0.04(2.77)a

F-test

1.95(19)a

  1. a Each result was the average of three separate determinations
  2. b The figures between brackets were the tabulated t and F values at P = 0.0526
  3. a- Ampoule contains20 mg/ 2 mL FRS. b-Tablets contain 40 mg FRS.