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Table 2 Biodistribution of [131I]iodocarvedilol in normal rats

From: Synthesis and biological evaluation of [131I]iodocarvedilol as a potential radiopharmaceutical for heart imaging

Organs &

Body fluids

% Injected dose/gram tissue at different time intervals, min

15

30

60

120

Blood

1.47 ± 0.13

0.21 ± 0.05

0.15 ± 0.02

0.20 ± 0.03

Bone

2.55 ± 0.17

1.43 ± 0.35

1.01 ± 0.21

0.8 ± 0.01

Muscle

4.17 ± 0.79

1.5 ± 0.04

1.2 ± 0.1

0.5 ± 0.02

Liver

12.74 ± 1.63

5.1 ± 0.15

2.5 ± 0.1

1.7 ± 0.1

Stomach

3.0 ± 0.03

2.6 ± 0.1

1.2 ± 0.16

1.1 ± 0.0

Intestine

6.4 ± 0.50

7.8 ± 0.3

8.8 ± 0.1

11.2 ± 0.03

Lung

5.5 ± 0.08

2.1 ± 0.12

1.3 ± 0.02

0.8 ± 0.01

Heart

24.5 ± 0.1

20.1 ± 0.3

19.6 ± 0.41

12.8 ± 0.25

Spleen

6.5 ± 0.31

2.9 ± 0.1

2.0 ± 0.02

1.7 ± 0.05

Kidney

30.2 ± 0.4

17.6 ± 0.6

10.6 ± 0.3

3.5 ± 0.06

Thyroid

1.1 ± 0.01

1.3 ± 0.01

1.2 ± 0.02

0.9 ± 0.05

  1. Values represent mean ± SEM