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Table 4 Robustness study of the proposed Ag–NPs method using pure (1000 ng/mL) of MOL

From: Earth-friendly-assessed silver-nanoparticles spectrophotometric method for rapid and sensitive analysis of Molnupiravir, an FDA-approved candidate for COVID-19: application on pharmaceutical formulation and dissolution test

Condition

Results

Recovery%a ± SD

Optimum conditionb

99.76 ± 1.12

AgNO3 (2 × 10–2 M) (0.40 mL)

98.45 ± 0.31

AgNO3 (2 × 10–2 M) (0.60 mL)

100.61 ± 0.67

PVP (0.14%) (0.60 mL)

99.03 ± 1.08

PVP (0.14%) (0.80 mL)

99.56 ± 0.69

NaOH (5 × 10–3 M) (0.40 mL)

98.22 ± 1.30

NaOH (5 × 10–3 M) (0.60 mL)

100.34 ± 0.71

Heating time (at 90 °C) (13 min)

98.13 ± 0.44

Heating time (at 90 °C) (17 min)

100.83 ± 0.96

  1. aMean of three determinations
  2. bOptimum condition as represented in Table 1