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Table 3 Assay parameters for the green analysis of MOL by the proposed Ag–NPs method

From: Earth-friendly-assessed silver-nanoparticles spectrophotometric method for rapid and sensitive analysis of Molnupiravir, an FDA-approved candidate for COVID-19: application on pharmaceutical formulation and dissolution test

Parameters

MOL

Concentration range

100–2000 (ng/mL)

Correlation coefficient

0.9999

Slope

0.0006

Intercept

0.0456

S.D of intercepta

0.0056

LODb

30 (ng/mL)

LOQb

90.77 (ng/mL)

Accuracy

 Mean ± SD

100.89 ± 0.60

 RSD%

0.60

 Er%c

0.89

Intra-day precisiond

 Mean ± SD

101.16 ± 1.12

 RSD%

1.11

 Er%c

1.16

Inter-day precisione

 Mean ± SD

100.58 ± 0.95

 RSD%

0.94

 Er%c

0.58

  1. aStandard deviation of intercept
  2. bLOD = (SD of the response/slope) × 3.3; LOQ = (SD of the response/slope) × 10
  3. cRelative error percentage
  4. dThe intra-day analysis, average of three different concentrations of MOL (500, 1000, and 1500 ng/mL) repeated three times within the day
  5. eThe inter-day analysis, average of three different concentrations of MOL (500, 1000, and 1500 ng/mL) repeated three times in three consecutive days