Table 3 Determination of Ofloxacin and Ornidazole in ORNI-O™ tablet by the developed spectrophotometric techniques and application of standard addition technique
Marketed drug **(ORNI-O™ tablet) | *Found % ± SD | Standard Addition Technique | *Recovery % of Standard Added | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
OFL | ORN | Conc. (μg/mL) | ||||||||
OFL | ORN | OFL | ORN | |||||||
Claimed | Standard added | Standard found | Claimed | Standard added | Standard found | |||||
Ratio difference spectrophotometric method | 101.10 ± 0.89 | 101.81 ± 1.14 | 5 | 10 | 10.14 | 12.5 | 10 | 10.12 | 101.38 | 101.16 |
5 | 5 | 5.08 | 12.5 | 15 | 15.40 | 101.60 | 102.69 | |||
5 | 3 | 2.9 | 12.5 | 5 | 5.12 | 99.92 | 102.49 | |||
Mean ± SD | 100.97 ± 0.91 | 102.11 ± 0.82 | ||||||||
Mean centering method | 101.05 ± 0.74 | 100.98 ± 0.76 | 5 | 10 | 10.06 | 12.5 | 10 | 10.06 | 100.67 | 100.68 |
5 | 5 | 4.99 | 12.5 | 15 | 14.84 | 99.84 | 99.96 | |||
5 | 3 | 2.98 | 12.5 | 5 | 4.98 | 99.49 | 99.78 | |||
Mean ± SD | 100.01 ± 0.60 | 99.81 ± 0.86 | ||||||||
Continuous wavelet transform | 100.59 ± 0.93 | 101.67 ± 0.42 | 5 | 10 | 9.87 | 12.5 | 10 | 10.15 | 98.77 | 101.57 |
5 | 5 | 4.96 | 12.5 | 15 | 14.86 | 99.26 | 99.11 | |||
5 | 3 | 3.03 | 12.5 | 5 | 4.98 | 100.85 | 99.73 | |||
Mean ± SD | 99.63 ± 1.08 | 100.13 ± 1.28 | ||||||||