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Table 1 Effect of experimental parameters on the number of theoretical plates

From: Micellar eco-friendly HPLC method for simultaneous analysis of ternary combination of aspirin, atorvastatin and ramipril: application to content uniformity testing

Parameter

Number of theoretical plates (N)

Resolution, RS

Selectivity, α

ASP

ATR

RAM

ASP/ATR

ATR/RAM

ASP/ATR

ATR/RAM

% Concentration n- propanol (v/v)

     

6

770

1271

746

2.9

4.2

3.5

2.78

8

510

931

1005

2.7

4.7

3.7

2.9

10

504

971

1317

2.7

4.6

3.1

2.7

12

465

892

1336

1.9

4.42

3.6

3.4

14

423

743

1402

3.5

3.6

16

2.7

15

567

1112

363

5.1

2.7

18

2.2

Concentration of SDS, M

     

0.05

467

1045

395

4.6

8

3

3.2

0.08

970

1766

1172

4.36

7.2

3.4

3.2

0.1

659

1229

1491

3

5

3.3

3.3

0.12

515

869

1485

2

4.44

4

3.5

0.15

480

859

1158

1.7

3.6

3.75

3.3

0.18

414

658

1143

1.5

2.2

6

3.5

pH of the medium

     

2.5

515

971

1485

3.2

5

3

2.66

3

651

606

1173

2.2

5.87

3.75

4.1

4

308

1207

207

0.32

6.35

1.17

26.76

5

Overlapped

343

    

6

Overlapped peaks

    

Flow rate, mL/min.

     

0.8

417

1094

forked

2.6

3.36

4.42

2.64

1

469

987

1380

2.38

4.4

4.16

3.12

1.2

458

974

1376

2.8

4.16

4.24

3.76

1.5

515

871

1485

2.54

4.2

4

3.37

2

473

964

1210

2.26

4.34

5.5

3.36