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Table 4 The penalty points of the proposed chromatographic method according to the analytical Eco-scale

From: Green adherent degradation kinetics study of Nirmatrelvir, an oral anti-COVID-19: characterization of degradation products using LC–MS with insilico toxicity profile

Reagents/Instruments

Penalty points (PPs)

Acetonitrile

3

NaOH

2

HCl

4

H2O2

4

Energy of HPLC

0

Occupational hazard

0

waste

3

PPs

16

Eco-scale score

84