Fig. 5From: Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitorsCrystal binding mode of (A) celecoxib, and predicted binding orientations of (B) 2d, (C) 2e, (D) 2f, and E (2i) visualized in COX-2 active site (PDB code 5KIR); ligands are shown in orange and amino acids are shown in blue. Only the interacting residues and their interaction patterns are shownBack to article page