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Table 3 Models fitting results

From: Application of Box-Behnken experimental design and response surface methodology for selecting the optimum RP-HPLC conditions for the simultaneous determination of methocarbamol, indomethacin and betamethasone in their pharmaceutical dosage form

Model term

Full quadratic models

R1 response

R2 response

R-squared

98.29

99.70

Adjusted R-squared

97.34

99.47

Predicted R-squared

93.83

98.59

P-value of lack of fit

0.621

0.380

  1. R1 = resolution response between methocarbamol and indomethacin
  2. R2 = resolution response between indomethacin and betamethasone
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BMC Chemistry

ISSN: 2661-801X

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