Fig. 3From: Application of Box-Behnken experimental design and response surface methodology for selecting the optimum RP-HPLC conditions for the simultaneous determination of methocarbamol, indomethacin and betamethasone in their pharmaceutical dosage formContour plots showing a, b the effects of Ratio (% of acetonitrile) and F (flow rate) on R1 and R2, respectively, c, d the effects of Ratio (% of acetonitrile) and pH of buffer on R1and R2, respectively, e, f the effects of F (flow rate) and pH of buffer on R1and R2, respectively. R1: resolution of indomethacin peak from methocarbamol peak. R2: resolution of betamethasone peak from indomethacin peakBack to article page