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Table 2 Data for antipromastigote activity (IC50) testing of the synthesized compounds

From: Synthesis, antimalarial, antileishmanial evaluation, and molecular docking study of some 3-aryl-2-styryl substituted-4(3H)-quinazolinone derivatives

Test compounds

Structure

IC50 values (µg/mL)

6

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0.021 ± 0.008

7

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3.248 ± 0.282

8

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3.326 ± 0.126

10

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0.196 ± 0.042

11

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0.185 ± 0.026

12

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1.842 ± 0.168

13

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2.265 ± 0.214

Miltefosine

–

3.191 ± 0.194

Amphotericin B

–

0.046 ± 0.009