Test compounds | Structure* | Dose (mg/kg) | % Parasitemia | % Suppression | Mean survival time (day) |
---|---|---|---|---|---|
6 | 17.95 | 39.22 ± 0.7 | 38.89 | 6.5 ± 0.3 | |
7 | 18.07 | 35.69 ± 0.69 | 45.3 | 6.9 ± 0.5 | |
8 | 19.21 | 19.57 ± 0.77 | 70.01 | 9.4 ± 0.37 | |
10 | 20.67 | 16.85 ± 0.39 | 74.18 | 9.8 ± 0.24 | |
11 | 17.17 | 25.27 ± 0.76 | 61.27 | 7.3 ± 0.54 | |
12 | 17.17 | 32 ± 0.5 | 50.96 | 7.6 ± 1.12 | |
13 | 18.63 | 24.13 ± 0.29 | 63.02 | 7.9 ± 0.3 | |
NC** | – | 1 mL/100 g | 65.25 ± 0.73 | 0.0 | 5.8 ± 0.17 |
CQ | – | 25 | 0 | 100 | ND |