From: A green and efficient synthetic methodology towards the synthesis of 1-allyl-6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives
Entry
Solvent
Triethylamine ratio
Ethylchloroformate ratio
4-Cl-aniline Ratio
% Yield
1
DMF
1.5
1.2
51
2
78
3
2.5
90
4
DMSO
87