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Table 2 Results of determination of the cited drugs in raw materials by the suggested method

From: Nitrogen and sulfur-doped carbon quantum dots as fluorescent nanoprobes for spectrofluorimetric determination of olanzapine and diazepam in biological fluids and dosage forms: application to content uniformity testing

Parameter

OLZ

DZP

Conc. taken (μM)

Conc. found (μM)

% recoverya

Conc. taken (μM)

Conc. found (μM)

% recoverya

 

5.0

4.85

97.12

1.0

0.98

98.23

25.0

24.65

98.60

10.0

9.80

98.00

50.0

49.58

99.16

25.0

24.96

99.84

85.0

87.17

102.56

50.0

50.22

100.45

115.0

114.01

99.15

75.0

74.85

99.80

185.0

184.45

99.70

100.0

100.01

100.01

200.0

200.30

100.14

 

Mean

 

99.49

 

99.39

 ± SD

1.66

1.02

% RSD

1.669

1.022

% error

0.62

0.42

 

Comparison method [53]

Comparison method [54]

    

Mean ± SD

100.30 ± 1.60

98.45 ± 1.02

    

Nc

3.0

3.0

    

t-value

0.72 (2.31)b

1.31 (2.36)b

    

F-value

1.07 (19.32)b

1.02 (19.30)b

    
  1. aAverage of three separate determinations
  2. bValues in parenthesis are the tabulated values of t and F at p = 0.05 [52]
  3. cNumber of samples
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BMC Chemistry

ISSN: 2661-801X

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