Compound | Cytotoxicity (IC50 ± SD) µM | |||
---|---|---|---|---|
MCF-7 | A549 | 5637 | MRC-5 | |
7a | 337.5 ± 9.6 | 190.2 ± 5.3 | 290.4 ± 7.6 | > 500 |
7b | 82.1 ± 5.6 | 67.3 ± 6.5 | 51.4 ± 2.5 | 201.9 ± 2.3 |
7c | 232.8 ± 11.8 | 347.6 ± 25.3 | 139.8 ± 5.3 | > 500 |
7d | 266.5 ± 21.7 | 178.2 ± 2.9 | 83.5 ± 4.9 | > 500 |
7e | 99.7 ± 4 | 113.2 ± 4.56 | 103.0 ± 2.1 | 339.0 ± 2.7 |
7f | 90.2 ± 7.1 | 227.5 ± 3.9 | 74.8 ± 2.4 | > 500 |
7g | 241.3 ± 46.3 | 292.3 ± 46.3 | 233.4 ± 39.4 | > 500 |
7h | 445.39 ± 42.0 | 175.2 ± 28.5 | 235.6 ± 1.0 | > 500 |
Cisplatin | 36.5 ± 1.9 | 14.8 ± 0.27 | 37.7 ± 1.9 | 45.2 ± 2.5 |