From: Development and validation of a novel Spectrofluorimetric method of oral anticoagulant Edoxaban via derivatization with 9-fluorenyl methyl chloroformate: green assessment of the method by Eco-Scale and ComplexGAPI
Eco-scale parameter
Penalty points
Diagram of complex gapi
Reagents
FMOC-Cl
2
Acetonitrile
Boric acid
Sodium chloride
Methanol
1
Instrument
Spectrofluorometry
0
pH meter
Sonicator
Occupational hazard waste:
10–100 mL
3
Degradation
∑penalty
13
Total score
87
Excellent greenness