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Table 8 Effect of compound 4e at different concentrations on HT-29 cell cycle progression after 48 h of incubation

From: Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity

Concentration

HepG2

Sub-G1

G0/G1

S

G2/M

2 µM

45.77 ± 2.45

30.68 ± 1.89

20.93 ± 0.18

4.40 ± 0.64

5 µM

47.10 ± 2.12

29.00 ± 0.41

21.10 ± 0.94

4.47 ± 0.44

10 µM

47.17 ± 2.40

32.16 ± 1.55

18.7 ± 0.12

3.98 ± 0.36

Control/vehicle

42.65 ± 1.61

31.16 ± 0.89

21.77 ± 0.39

4.40 ± 0.36

  1. The data presented are the mean ± SE of three independent experiments