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Table 7 Effect of compound 4c at different concentrations on HT-29 cell cycle progression after 48 h of incubation

From: Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity

Concentration

HepG2

Sub-G1

G0/G1

S

G2/M

6 µM

47.79 ± 0.75

29.23 ± 2.18

21.67 ± 0.32

1.65 ± 0.11

10 µM

48.46 ± 2.16

31.65 ± 2.78

20.63 ± 0.45

4.56 ± 1.12

15 µM

47.50 ± 1.48

27.50 ± 1.63

22.3 ± 0.27

1.31 ± 0.02

Control/vehicle

42.65 ± 1.61

31.16 ± 0.89

21.77 ± 0.39

4.40 ± 0.36

  1. The data presented are the mean ± SE of three independent experiments
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BMC Chemistry

ISSN: 2661-801X

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