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Table 2 Determination of PAR, ASP and DIPH in synthetic mixtures by the proposed spectrophotometric methods

From: Eco-friendly resolution of spectrally overlapping signals of a combined triple-action over-the-counter pharmaceutical formulation for symptomatic management of COVID-19 pandemic: application to content uniformity testing

Ratio (PAR:ASP:DIPH)

Claimed concentration (μg/mL)

% Recoverya

D1 method

DWRS method

DD-RD method

PAR

ASP

DIPH

PAR

ASP

DIPH

1:1:1

10.0

10.0

10.0

99.42

98.08

100.18

1:1:0.15b

10.0

10.0

1.5

99.71

98.58

100.00

4:1:4

20.0

5.0

20.0

101.97

100.17

98.77

3:2:1

15.0

10.0

5.0

101.96

99.56

99.18

1:3:1

5.0

15.0

5.0

101.86

100.01

100.35

Mean ± SD

 

100.98 ± 1.300

99.28 ± 0.914

99.70 ± 0.684

  1. aAverage of three determinations
  2. bDosage form ratio