Table 8 Intra- and inter-day precision and stability results of XIP and VAL QC samples samples
|  | Drugs | Concentrations (µg/mL) | Meana ± SD | CV (%) |
|---|---|---|---|---|
Intra-day runs (n = 3) | XIP | 50 | 100.98 ± 0.12 | 0.12 |
25 | 98.91 ± 0.19 | 0.19 | ||
12.5 | 98.97 ± 0.37 | 0.38 | ||
VAL | 50 | 100.53 ± 0.13 | 0.1 | |
25 | 99.57 ± 0.16 | 0.17 | ||
12.5 | 98.06 ± 0.34 | 0.35 | ||
Inter-day runs (n = 3) | XIP | 50 | 100.8 ± 0.06 | 0.06 |
25 | 98.92 ± 0.31 | 0.32 | ||
12.5 | 99.15 ± 0.37 | 0.38 | ||
VAL | 50 | 100.75 ± 0.08 | 0.08 | |
25 | 99.84 ± 0.3 | 0.3 | ||
12.5 | 98.19 ± 0.52 | 0.53 | ||
3 Freeze–thaw cycles at − 20 °C (n plasma = 3) | XIP | 20 | 93.02 ± 0.38 | 0.41 |
15 | 95.62 ± 0.83 | 0.87 | ||
5 | 98.31 ± 0.62 | 0.63 | ||
VAL | 20 | 87.72 ± 0.21 | 0.24 | |
15 | 85 ± 0.86 | 1.02 | ||
5 | 99.77 ± 2.17 | 2.17 |