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Table 4 Pharmacokinetics parameters of Cabergoline after a single dose of test product (2 × 0.5 mg) film coated tablets and Dostinex (2 × 0.5 mg) tablets (reference product)

From: A validated LC–MS/MS method for analysis of Cabergoline in human plasma with its implementation in a bioequivalent study: investigation of method greenness

 

Items

Cmax (pg/mL)

Tmax (h)

AUC0-t (pg·h/mL)

Kel (1/h)

t½ (h)

Test product (2 × 0.5 mg) tablets

Mean

29.37

2.17

734.38

0.017

131.221

CV

± 7.5

± 0.2

± 174.66

± 0.012

± 33.506

Reference product (2 × 0.5 mg) tablets

Mean

30.20

2.33

755.62

0.02

80.99

CV

± 3.40

± 0.25

± 143.29

0.02

± 13.46